CUCURBITURIL COMPOUND AND MEDICAL USE THEREOF

WIPO Patent Application WO/2024/099434

A1

The present disclosure relates to a cucurbituril compound and the medical use thereof. Specifically, the present disclosure relates to a compound as shown in formula (I), a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition comprising same and the use thereof as a therapeutic agent, in particular the use thereof in the treatment or prevention of proliferative diseases, cardiovascular-related diseases or blood cancer and the use thereof in the reversal of drug-induced neuromuscular blocking and/or anesthesia, wherein each substituent is as defined in the description. (I)

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ZHU LINGJIAN (CN)
REN WENMING (CN)
ZOU YANG (CN)
LEI SHENGHUI (CN)
ZHU DAN (CN)
HUANG JIAN (CN)

PCT/CN2023/131007

May 16, 2024

November 10, 2023

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SHANGHAI SENHUI MEDICINE CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)

C07D487/22; A61K31/407; A61K31/4188; A61P21/02; A61P23/00; A61P35/00

GE CHENG & CO., LTD (CN)

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