Title:
TEAD INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2024/099435
Kind Code:
A1
Abstract:
The present invention provides a compound represented by formula I, and a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt or a prodrug thereof. As a TEAD inhibitor, the compound can significantly inhibit the activity of TEAD transcription, and can be used for preventing and/or treating diseases related to increased TEAD expression.
Inventors:
ZHANG XUEJUN (CN)
ZANG YANG (CN)
YANG HUI (CN)
LI CHAO (CN)
LI JINPING (CN)
LI LIE (CN)
YANG JUN (CN)
ZHU SHENGJI (CN)
LI YUQIONG (CN)
ZANG YANG (CN)
YANG HUI (CN)
LI CHAO (CN)
LI JINPING (CN)
LI LIE (CN)
YANG JUN (CN)
ZHU SHENGJI (CN)
LI YUQIONG (CN)
Application Number:
PCT/CN2023/131008
Publication Date:
May 16, 2024
Filing Date:
November 10, 2023
Export Citation:
Assignee:
WUHAN HUMANWELL INNOVATIVE DRUG RES AND DEVELOPMENT CENTER LIMITED COMPANY (CN)
International Classes:
C07D233/64; A61K31/18; A61K31/415; A61K31/4164; A61P35/00; A61P35/02; C07D231/12; C07D257/04; C07D401/12; C07D413/12; C07D487/04
Domestic Patent References:
| WO2020243415A2 | 2020-12-03 | |||
| WO2022177869A1 | 2022-08-25 | |||
| WO2022159986A1 | 2022-07-28 | |||
| WO2020243423A1 | 2020-12-03 | |||
| WO2021247634A1 | 2021-12-09 | |||
| WO2019040380A1 | 2019-02-28 |
Foreign References:
| CN115594680A | 2023-01-13 | |||
| CN115466243A | 2022-12-13 |
Attorney, Agent or Firm:
BEIJING DOCVIT LAW FIRM (CN)
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