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Title:
CYCLIC AMINE COMPOUND AND CCR3 INHIBITORY DRUG CONTAINING THE SAME AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2003/072545
Kind Code:
A1
Abstract:
A cyclic amine compound represented by the general formula (1): [wherein A is a group which is selected from the group consisting of substituted aryls, substituted heterocyclic groups, and substituted cycloalkyls, has at least one substituent X, and may have at least one substituent Y (wherein the substituent X is selected from the group consisting of HO-(C1-6 alkyl), HO-(C2-6 alkyl)-O-(C1-6 alkyl), HOOC-(C1-6 alkyl), (C1-6 alkyl)-OCO-(C1-6 alkyl), NH2CO-(C1-6 alkyl), (C1-3 alkyl)2NCO-(C1-6 alkyl), (C1-3 alkyl)-CONH-(C1-6 alkyl), HOOC-(C1-6 alkyl)-O-(C1-6 alkyl), etc., and the substituent Y is selected from the group consisting of halogeno, C1-3 alkyl, OH, methoxy, CN, and CF3)] or a pharmaceutically acceptable salt of the compound.

Inventors:
IMAOKA TAKAYUKI (JP)
KAWAMURA KUNIAKI (JP)
KANEKO MASAYUKI (JP)
KOZONO HIDEKI (JP)
MORIHIRA KOICHIRO (JP)
KUBOTA HIROKAZU (JP)
MOROKATA TATSUAKI (JP)
KANEEDA MASANOBU (JP)
Application Number:
PCT/JP2003/002227
Publication Date:
September 04, 2003
Filing Date:
February 27, 2003
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
YAMANOUCHI PHARMA CO LTD (JP)
IMAOKA TAKAYUKI (JP)
KAWAMURA KUNIAKI (JP)
KANEKO MASAYUKI (JP)
KOZONO HIDEKI (JP)
MORIHIRA KOICHIRO (JP)
KUBOTA HIROKAZU (JP)
MOROKATA TATSUAKI (JP)
KANEEDA MASANOBU (JP)
International Classes:
A61K31/40; A61K31/404; A61K31/416; A61K31/4178; A61K31/4184; A61K31/4439; A61K31/506; A61P1/04; A61P11/00; A61P11/06; A61P17/00; A61P27/16; A61P29/00; A61P33/00; A61P37/08; A61P43/00; C07D207/14; (IPC1-7): C07D207/14; A61K31/40; A61K31/404; A61K31/416; A61K31/4178; A61K31/4184; A61K31/4439; A61K31/506; A61P1/04; A61P11/00; A61P11/06; A61P17/00; A61P27/16; A61P29/00; A61P33/00; A61P37/08; A61P43/00; C07D401/12; C07D403/12
Domestic Patent References:
WO2001028987A12001-04-26
Attorney, Agent or Firm:
Hiraki, Yusuke (17-1 Toranomon 1-chom, Minato-ku Tokyo, JP)
Shimamura, Naomi (Omiya-ku Saitama-shi, Saitama, JP)
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