Title:
CYTOKINE PRODUCTION SUPPRESSING COMPOSITION CONTAINING D-ALLOSE AS ACTIVE COMPONENT, AND METHOD OF TREATING OR PREVENTING DISEASE ASSOCIATED WITH CYTOKINE OVERPRODUCTION USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/209593
Kind Code:
A1
Abstract:
The present invention provides a cytokine production suppressing composition containing D-allose as an active component. The present invention further provides a method of treating or preventing diseases associated with cytokine overproduction in a subject, said method involving dosing the subject with the cytokine production suppressing composition containing D-allose as an active component.
Inventors:
HOSHINO KATSUAKI (JP)
TAKAO KENJIRO (JP)
IZUMORI KEN (JP)
TAKAO KENJIRO (JP)
IZUMORI KEN (JP)
Application Number:
PCT/JP2022/009524
Publication Date:
October 06, 2022
Filing Date:
March 04, 2022
Export Citation:
Assignee:
UNIV KAGAWA NAT UNIV CORP (JP)
International Classes:
A61K31/7004; A23L33/125; A61K31/7008; A61K31/7012; A61P37/02; A61P43/00
Other References:
HUANG TAO; GAO DAKUAN; HEI YUE; ZHANG XIN; CHEN XIAOYAN; FEI ZHOU: "D-allose protects the blood brain barrier through PPARγ-mediated anti-inflammatory pathway in the mice model of ischemia reperfusion injury", BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 1642, 19 April 2016 (2016-04-19), NL , pages 478 - 486, XP029567662, ISSN: 0006-8993, DOI: 10.1016/j.brainres.2016.04.038
ANONYMOUS: "A candy way to say no to pain: Rare sugar-based therapy for inflammation and arthritis:D-Allose, an aldohexose sugar and C-3 epimer of glucose, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, at", GENOME DISCOVERY, DR BOOMI'S GENOME-2-BIO-MEDICINE DISCOVERY CENTRE (GMBD), 18 March 2018 (2018-03-18), pages 1 - 6, XP055972831, Retrieved from the Internet
ANONYMOUS: "A candy way to say no to pain: Rare sugar-based therapy for inflammation and arthritis:D-Allose, an aldohexose sugar and C-3 epimer of glucose, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, at", GENOME DISCOVERY, DR BOOMI'S GENOME-2-BIO-MEDICINE DISCOVERY CENTRE (GMBD), 18 March 2018 (2018-03-18), pages 1 - 6, XP055972831, Retrieved from the Internet
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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