Title:
DENDRITIC CELL-BASED CANCER VACCINES AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/240658
Kind Code:
A1
Abstract:
The present invention is directed to methods for preparing a recombinant cell and a fusion cell for a dendritic cell-based cancer vaccine, wherein the recombinant cell and the fusion cell comprise DNA of a cancer cell. The present invention is also directed to the fusion cells comprising genomic DNA of a tumor cell, a method for fusing human dendritic cells and fibroblast cells, a pharmaceutical composition comprising the fusion cell, and a method of preventing cancer comprising administering to a cancer patient an effective amount of the fusion cells.
Inventors:
SAKUMA SADATOSHI (JP)
OSONO MICHIYO (JP)
ISHIKAWA FUTOSHI (JP)
UOZUMI TOSHIKI (JP)
OKA ERIKO (JP)
MURATA HIROKI (JP)
YANG HUI YU (JP)
OSONO MICHIYO (JP)
ISHIKAWA FUTOSHI (JP)
UOZUMI TOSHIKI (JP)
OKA ERIKO (JP)
MURATA HIROKI (JP)
YANG HUI YU (JP)
Application Number:
PCT/JP2019/020891
Publication Date:
December 03, 2020
Filing Date:
May 27, 2019
Export Citation:
Assignee:
KINKO CAPITAL CO LTD (JP)
International Classes:
C12N5/00; A61K38/00; A61K48/00; A61P35/00; C12N15/09
Domestic Patent References:
| WO2005084387A2 | 2005-09-15 |
Other References:
HUSCHTSCHA, LILY I. ET AL.: "Enhanced isolation of fibroblasts from human skin explants", BIOTECHNIQUES, vol. 53, 2012, pages 239 - 244, XP055211032, DOI: 10.2144/0000113939
M J SIKORA, J N THIBERT, J SALTER, M DOWSETT, M D JOHNSON & J M RAE: "High-efficiency genotype analysis from formalin-fixed, paraffin-embedded tumor tissues", THE PHARMACOGENOMICS JOURNAL, vol. 11, 2011, pages 348 - 358, XP055764675
M J SIKORA, J N THIBERT, J SALTER, M DOWSETT, M D JOHNSON & J M RAE: "High-efficiency genotype analysis from formalin-fixed, paraffin-embedded tumor tissues", THE PHARMACOGENOMICS JOURNAL, vol. 11, 2011, pages 348 - 358, XP055764675
Attorney, Agent or Firm:
YOSHIKAWA, Toshio (JP)
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