Title:
DENDRITIC CELL CANCER VACCINE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/115676
Kind Code:
A1
Abstract:
Provided is a dendritic cell cancer vaccine, which is obtained by delivery particles loaded with cell components activating dendritic cells in vitro, wherein the delivery particles are nanoparticles and/or microparticles, the cell components are derived from water-soluble components and/or non-water-soluble components of cancer cells and/or tumor tissue cells, and activation is a process in which the delivery particles loaded with the cell components and the dendritic cells are co-incubated.
Inventors:
LIU MI (CN)
DIAO LU (CN)
DIAO LU (CN)
Application Number:
PCT/CN2022/073141
Publication Date:
June 29, 2023
Filing Date:
January 21, 2022
Export Citation:
Assignee:
SUZHOU ERSHENG BIOMEDICAL CO LTD (CN)
International Classes:
C12N5/0784; A61K9/14; A61K39/00; A61K39/39; A61K39/395; A61P35/00
Domestic Patent References:
| WO2021233237A1 | 2021-11-25 |
Foreign References:
| US20140065173A1 | 2014-03-06 | |||
| CN112245574A | 2021-01-22 | |||
| CN113440605A | 2021-09-28 |
Other References:
PATI, R. ET AL.: "Nanoparticle Vaccines Against Infectious Diseases", FRONTIERS IN IMMUNOLOGY, vol. 9, no. 5, 4 October 2018 (2018-10-04), XP055818459, DOI: 10.3389/fimmu.2018.02224
FIRDESSA-FITE REBUMA, CREUSOT RÉMI J.: "Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy", MOLECULAR THERAPY- METHODS & CLINICAL DEVELOPMENT, NATURE PUBLISHING GROUP, GB, vol. 16, 1 March 2020 (2020-03-01), GB , pages 50 - 62, XP093073910, ISSN: 2329-0501, DOI: 10.1016/j.omtm.2019.10.015
XUE SONG, SUN YING-HAO, GAO JIAN-PING, GE JING-PING, XU CHUAN-LIANG, ZHU XUE-JUN, FAN ZHEN-FANG: "Immunotherapy of mouse renal cell carcinoma with tumor lysate-pulsed dendritic cells", YIXUE YANJIUSHENG XUEBAO [JOURNAL OF MEDICAL POSTGRADUATES], vol. 23, no. 5, 31 May 2010 (2010-05-31), pages 477 - 481, XP093073912, ISSN: 1008-8199, DOI: 10.16571/j.cnki.1008-8199.2010.05.019
FIRDESSA-FITE REBUMA, CREUSOT RÉMI J.: "Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy", MOLECULAR THERAPY- METHODS & CLINICAL DEVELOPMENT, NATURE PUBLISHING GROUP, GB, vol. 16, 1 March 2020 (2020-03-01), GB , pages 50 - 62, XP093073910, ISSN: 2329-0501, DOI: 10.1016/j.omtm.2019.10.015
XUE SONG, SUN YING-HAO, GAO JIAN-PING, GE JING-PING, XU CHUAN-LIANG, ZHU XUE-JUN, FAN ZHEN-FANG: "Immunotherapy of mouse renal cell carcinoma with tumor lysate-pulsed dendritic cells", YIXUE YANJIUSHENG XUEBAO [JOURNAL OF MEDICAL POSTGRADUATES], vol. 23, no. 5, 31 May 2010 (2010-05-31), pages 477 - 481, XP093073912, ISSN: 1008-8199, DOI: 10.16571/j.cnki.1008-8199.2010.05.019
Attorney, Agent or Firm:
CENTRAL SOUTH WELL INTELLECTUAL PROPERTY OFFICE (CN)
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