DENDRITIC POLYGLYCOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Title:

DENDRITIC POLYGLYCOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2019/001473

Kind Code:

A1

Abstract:

Provided are a dendritic polyglycol derivative, a preparation method therefor, and an application thereof. The dendritic polyglycol derivative has a structure of formula (I), a plurality of terminal functional groups, and better water solubility when compared to straight-chain polyglycols. The dendritic polyglycol derivative can resolve the issue of insufficient water solubility caused by an increase in load when polyglycols are used to modify insoluble drugs. The preparation method further provided for the dendritic polyglycol derivative has mild reaction conditions, and is environmentally friendly, low cost, and easy to industrialize.

Inventors:

ZHU HUI (CN)
LIN MEINA (CN)
ZHAO XUAN (CN)

Application Number:

PCT/CN2018/093134

Publication Date:

January 03, 2019

Filing Date:

June 27, 2018

Export Citation:

Click for automatic bibliography generation Help

Assignee:

JENKEM TECH CO LTD BEIJING (CN)

International Classes:

C07C43/11; A61K47/50; A61K47/60; C07C41/18; C07C213/02; C07C213/08; C07C217/08; C08G65/48

Foreign References:

CN101389354A	2009-03-18
CN102367291A	2012-03-07
CN106146325A	2016-11-23
CN104387577A	2015-03-04

Attorney, Agent or Firm:

BEIJING BRIGHT IP AGENCY CO., LTD. (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: BRANCHED POLYGLYCOL EPOXY DERIVATIVE CROSS-LINKED SODIUM HYALURONATE GEL, PREPARATION THEREFOR, AND ...

Next Patent: CHIMERIC ANTIBODY IMMUNE EFFCTOR CELL ENGAGERS AND METHODS OF USE THEREOF