Title:
DENTAL TREATMENT COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2020/090965
Kind Code:
A1
Abstract:
Provided is a dental treatment composition which exhibits excellent handleability and can facilitate formation of dentin. This dental treatment composition contains a compound (I) having a structure represented by general formula (1) and a dentin-forming agent (II). (In formula (1), R1 is a hydrocarbon group, A is a -C(=O)-R2-O- group (R2 is a specific alkylene group), B is a -C(=O)-C(-R3)(-R4)-O- group (R3 is a hydrogen atom or a hydrocarbon group, and R4 is a hydrocarbon group), s is a number that is 0 or greater, m is 0-800, and n is 0-700. However, m and n cannot both be 0.)
Inventors:
OKAMOTO MOTOKI (JP)
TAKAHASHI YUSUKE (JP)
HAYASHI MIKAKO (JP)
KANIE KEI (JP)
OGATA AIKA (JP)
NARITA YUJI (JP)
KATO RYUJI (JP)
EBARA MITSUHIRO (JP)
UTO KOICHIRO (JP)
TAKAHASHI YUSUKE (JP)
HAYASHI MIKAKO (JP)
KANIE KEI (JP)
OGATA AIKA (JP)
NARITA YUJI (JP)
KATO RYUJI (JP)
EBARA MITSUHIRO (JP)
UTO KOICHIRO (JP)
Application Number:
PCT/JP2019/042742
Publication Date:
May 07, 2020
Filing Date:
October 31, 2019
Export Citation:
Assignee:
UNIV OSAKA (JP)
UNIV NAGOYA NAT UNIV CORP (JP)
NAT INST MATERIALS SCIENCE (JP)
UNIV NAGOYA NAT UNIV CORP (JP)
NAT INST MATERIALS SCIENCE (JP)
International Classes:
A61K6/838; A61K6/891; A61P1/02; C07K7/06; C08G63/08; C08L67/00; C08L89/00
Domestic Patent References:
| WO2014061341A1 | 2014-04-24 | |||
| WO2010113800A1 | 2010-10-07 |
Foreign References:
| JPH11501029A | 1999-01-26 |
Other References:
SUWA, F. ET AL.: "Ability of hydroxyapatite-bone morphogenetic (corrected from morphologenetic) protein (BMP) complex to induce dentin formation in dogs", OKAJIMAS FOLIA ANATOMICA JAPONICA, vol. 70, no. 5, 1993, pages 195 - 201, XP55704452
KOIKE, TOSHIYUKI ET AL.: "Reparative dentin induction with calcified algae derived hydroxyapatite-BMP composite in rat maxillary molars", THE DENTAL JOURNAL OF HEALTH SCIENCES UNIVERSITY OF HOKKAIDO, vol. 29, no. 2, pages 183 - 189, Retrieved from the Internet
NOGUCHI, H. ET AL., BONE CONDUCTIVE AND INDUCTIVE EFFECTS OF POLY(L-LACTID AND EPSILON-CAPROLACTONE)/ HYDROXYAPATITE COMPOSITES AND BONE MORPHOGENETIC PROTEIN-2 IN RATS, vol. 35, no. 2, 2008, pages 147 - 154, XP55704449, Retrieved from the Internet
KANIE, K. ET AL.: "Screening of Osteogenic- Enhancing Short Peptides from BMPs for Biomimetic Material Applications", MATERIALS, vol. 9, no. 9, 2016, pages 1 - 17, XP55704446
HANAFY, A. K. ET AL.: "Nano Hydroxyapatite & Mineral Trioxide Aggregate Efficiently Promote Odontogenic Differentiation of Dental Pulp Stem Cells", OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES, vol. 6, no. 9, 25 September 2018 (2018-09-25), pages 1727 - 1731, XP55704440
KOIKE, TOSHIYUKI ET AL.: "Reparative dentin induction with calcified algae derived hydroxyapatite-BMP composite in rat maxillary molars", THE DENTAL JOURNAL OF HEALTH SCIENCES UNIVERSITY OF HOKKAIDO, vol. 29, no. 2, pages 183 - 189, Retrieved from the Internet
NOGUCHI, H. ET AL., BONE CONDUCTIVE AND INDUCTIVE EFFECTS OF POLY(L-LACTID AND EPSILON-CAPROLACTONE)/ HYDROXYAPATITE COMPOSITES AND BONE MORPHOGENETIC PROTEIN-2 IN RATS, vol. 35, no. 2, 2008, pages 147 - 154, XP55704449, Retrieved from the Internet
KANIE, K. ET AL.: "Screening of Osteogenic- Enhancing Short Peptides from BMPs for Biomimetic Material Applications", MATERIALS, vol. 9, no. 9, 2016, pages 1 - 17, XP55704446
HANAFY, A. K. ET AL.: "Nano Hydroxyapatite & Mineral Trioxide Aggregate Efficiently Promote Odontogenic Differentiation of Dental Pulp Stem Cells", OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES, vol. 6, no. 9, 25 September 2018 (2018-09-25), pages 1727 - 1731, XP55704440
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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