DEUTERATED COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

DEUTERATED COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/169480

Kind Code:

A9

Abstract:

Provided are a deuterated compound represented by formula IA or a pharmaceutically acceptable salt thereof, a preparation method therefor and a use thereof. Some deuterated compounds have a half-life period of up to 2-4 times that of BVD-523, therefore have a longer action time in in-vivo metabolism, generate more effective clinical application values, and are expected to solve the side effects caused by metabolic defects at present in BVD-523.

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Inventors:

YAO ZHENGLIN (CN)
YIN LEI (CN)

Application Number:

PCT/CN2023/080351

Publication Date:

January 11, 2024

Filing Date:

March 08, 2023

Export Citation:

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Assignee:

GAN & LEE PHARMACEUTICALS CO LTD (CN)

International Classes:

C07D401/04; A61K31/4439; A61P35/00

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