Title:
DEUTERATED PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2024/099241
Kind Code:
A1
Abstract:
The present invention relates to a deuterated pyrimidine derivative represented by formula I or a pharmaceutically acceptable salt, an isomer, a metabolite, a prodrug, a solvate, or a hydrate thereof. The present invention further relates to pharmaceutical compositions comprising a pharmaceutically acceptable carrier and the deuterated pyrimidine derivative or pharmaceutically acceptable salt, isomer, metabolite, prodrug, solvate, or hydrate thereof. The compound represented by general formula I of the present invention serves as a BTK inhibitor, is a prophylactic and/or therapeutic agent for BTK-related diseases, and has a good therapeutic effect on allergic diseases, autoimmune diseases, inflammatory diseases, thromboembolic diseases, or cancers.
Inventors:
BAO RONGXIAO (CN)
Application Number:
PCT/CN2023/129825
Publication Date:
May 16, 2024
Filing Date:
November 04, 2023
Export Citation:
Assignee:
TIANJIN ZHENGCHENG MEDICAL TECH CO LTD (CN)
International Classes:
C07D401/12; A61K31/506; A61P35/00; A61P37/00
Attorney, Agent or Firm:
BEIJING JUNYOU INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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