Title:
DIAGNOSIS OF FEBRILE NEUTROPENIA BY MEASURING PRESEPSIN
Document Type and Number:
WIPO Patent Application WO/2014/178383
Kind Code:
A1
Abstract:
A method for detecting febrile neutropenia in a cancer patient by using as an index the sCD14-ST concentration in a blood specimen that is obtained from the cancer patient, and a method for selecting a febrile neutropenia patient to whom an antibiotic is to be administered by using as an index the aforesaid sCD14-ST concentration.
Inventors:
NAKAMAE HIROHISA (JP)
KOH HIDEO (JP)
KOH HIDEO (JP)
Application Number:
PCT/JP2014/061897
Publication Date:
November 06, 2014
Filing Date:
April 28, 2014
Export Citation:
Assignee:
MOCHIDA PHARM CO LTD (JP)
International Classes:
G01N33/68; C07K16/30; C12Q1/04; G01N33/53; G01N33/80
Domestic Patent References:
| WO2004044005A1 | 2004-05-27 |
Foreign References:
| US20120238460A1 | 2012-09-20 |
Other References:
MINORU YOSHIDA: "Rinshoi ga Shitte Okubeki Kokin'yaku no Tsukaikata III Tokushu Byotai Tokushu Bumon deno Tsukaikata Kochukyu Genshoji no Hatsunetsu", SHINDAN TO CHIRYO, vol. 96, no. 1, 2008, pages 103 - 109
URBONAS, VINCAS ET AL.: "The predictive value of soluble biomarkers ( CD 14 subtype, interleukin-2 receptor, human leucocyte antigen-G) and procalcitonin in the detection of bacteremia and sepsis in pediatric oncology patients with chemotherapy-induced febrile neutropenia", CYTOKINE, vol. 62, no. 1, 17 March 2013 (2013-03-17), pages 34 - 37
KOH, HIDEO ET AL.: "Diagnostic Value Of Serum Level Of Soluble CD 14-Subtype In Febrile Neutropenia In Patients With Hematologic Disorders", BLOOD, vol. 122, no. 21, 15 November 2013 (2013-11-15), pages 4718
WONG, MICHELLE ET AL.: "Microbial Translocation Contribute to Febrile Episodes in Adults with Chemotherapy-Induced Neutropenia", PLOS ONE, vol. 8, no. 7, 16 July 2013 (2013-07-16), pages E68056
URBONAS, VINCAS ET AL.: "The predictive value of soluble biomarkers ( CD 14 subtype, interleukin-2 receptor, human leucocyte antigen-G) and procalcitonin in the detection of bacteremia and sepsis in pediatric oncology patients with chemotherapy-induced febrile neutropenia", CYTOKINE, vol. 62, no. 1, 17 March 2013 (2013-03-17), pages 34 - 37
KOH, HIDEO ET AL.: "Diagnostic Value Of Serum Level Of Soluble CD 14-Subtype In Febrile Neutropenia In Patients With Hematologic Disorders", BLOOD, vol. 122, no. 21, 15 November 2013 (2013-11-15), pages 4718
WONG, MICHELLE ET AL.: "Microbial Translocation Contribute to Febrile Episodes in Adults with Chemotherapy-Induced Neutropenia", PLOS ONE, vol. 8, no. 7, 16 July 2013 (2013-07-16), pages E68056
Attorney, Agent or Firm:
KOBAYASHI, Hiroshi et al. (JP)
Kobayashi 浩 (JP)
Kobayashi 浩 (JP)
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