Title:
DISSOLVING AGENT
Document Type and Number:
WIPO Patent Application WO/2021/162106
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a dissolving agent which improves the solubility of a compound such as curcumin that contains an aromatic ring without changing the structure of the compound. The present invention is a compound which is represented by general formula (1).
(In the formula, R1 represents an alkyl group having from 7 to 24 carbon atoms or an alkenyl group; A1 represents an optionally substituted aryl group; Z1 represents a single bond, an alkylene group having from 1 to 6 carbon atoms, or an alkenylene group having from 2 to 5 carbon atoms; and Z2 represents a divalent linking group.)
Inventors:
HARASHIMA HIDEYOSHI (JP)
SATO YUSUKE (JP)
ABBASI SAED AMJAD YOUSEF (JP)
YAMASHITA SHINJI (JP)
HIGASHINO HARUKI (JP)
SATO YUSUKE (JP)
ABBASI SAED AMJAD YOUSEF (JP)
YAMASHITA SHINJI (JP)
HIGASHINO HARUKI (JP)
Application Number:
PCT/JP2021/005310
Publication Date:
August 19, 2021
Filing Date:
February 12, 2021
Export Citation:
Assignee:
UNIV HOKKAIDO NAT UNIV CORP (JP)
KAWASAKI INST OF INDUSTRIAL PROMOTION (JP)
KAWASAKI INST OF INDUSTRIAL PROMOTION (JP)
International Classes:
A61P35/00; A61K31/12; A61K31/337; A61K31/353; A61K31/695; A61K47/14; C07C69/618
Foreign References:
| CN106588665B | 2019-08-20 | |||
| US20070077214A1 | 2007-04-05 | |||
| US20160332950A1 | 2016-11-17 |
Other References:
JING QUAN; YANG YU; CHRISTOPHER BRANFORD-WHITE; GARETH R. WILLIAMS; DENG-GUANG YU; WEI NIE; LI-MIN ZHU;: "Preparation of ultrafme fast-dissoiving feruloyl-oleyl-glycerol-loaded polyvinylpyrrolidone fiber mats via electrospinning, Colloids and Surfaces", COLLOIDS AND SURFACES B: BIOINTERFACES, vol. 88, no. 1, 4 July 2011 (2011-07-04), pages 304 - 309, XP028275358, ISSN: 0927-7765, DOI: 10.1016/j.colsurfb.2011.07.006
KARBOUNE, S. , SAFARI, M. , LUE, B.M. , YEBOAH, F.K. , KERMASHA, S.: "Lipase-catalyzed biosynthesis of cinnamoylated lipids in a selected organic solvent medium", JOURNAL OF BIOTECHNOLOGY, vol. 119, no. 3, 29 September 2005 (2005-09-29), pages 281 - 290, XP005064045, ISSN: 0168-1656, DOI: 10.1016/j.jbiotec.2005.03.012
JO JIN CHUL; KIM HYUNG KWOUN: "Production of cinnamoyl lipids using immobilized proteus vulgaris K80 lipase and an evaluation of their antioxidant activity", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, vol. 129, 21 April 2016 (2016-04-21), pages 54 - 60, XP029544442, ISSN: 1381-1177, DOI: 10.1016/j.molcatb.2016.04.008
KARBOUNE, S. ; ST-LOUIS, R. ; KERMASHA, S.: "Enzymatic synthesis of structured phenolic lipids by acidolysis of flaxseed oil with selected phenolic acids", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, vol. 52-53, 1 June 2008 (2008-06-01), pages 96 - 105, XP022586924, ISSN: 1381-1177, DOI: 10.1016/j.molcatb.2007.10.015
KUZNETSOVA NATALIA R.; SEVRIN CHANTAL; LESPINEUX DAVID; BOVIN NICOLAI V.; VODOVOZOVA ELENA L.; MÉSZÁROS TAMÁS; SZEBENI JANOS; GRAN: "Hemocompatibility of liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the lipid bilayer", JOURNAL OF CONTROLLED RELEASE, vol. 160, no. 2, 10 June 2012 (2012-06-10), pages 394 - 400, XP028926617, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2011.12.010
KARBOUNE, S. , SAFARI, M. , LUE, B.M. , YEBOAH, F.K. , KERMASHA, S.: "Lipase-catalyzed biosynthesis of cinnamoylated lipids in a selected organic solvent medium", JOURNAL OF BIOTECHNOLOGY, vol. 119, no. 3, 29 September 2005 (2005-09-29), pages 281 - 290, XP005064045, ISSN: 0168-1656, DOI: 10.1016/j.jbiotec.2005.03.012
JO JIN CHUL; KIM HYUNG KWOUN: "Production of cinnamoyl lipids using immobilized proteus vulgaris K80 lipase and an evaluation of their antioxidant activity", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, vol. 129, 21 April 2016 (2016-04-21), pages 54 - 60, XP029544442, ISSN: 1381-1177, DOI: 10.1016/j.molcatb.2016.04.008
KARBOUNE, S. ; ST-LOUIS, R. ; KERMASHA, S.: "Enzymatic synthesis of structured phenolic lipids by acidolysis of flaxseed oil with selected phenolic acids", JOURNAL OF MOLECULAR CATALYSIS B: ENZYMATIC, vol. 52-53, 1 June 2008 (2008-06-01), pages 96 - 105, XP022586924, ISSN: 1381-1177, DOI: 10.1016/j.molcatb.2007.10.015
KUZNETSOVA NATALIA R.; SEVRIN CHANTAL; LESPINEUX DAVID; BOVIN NICOLAI V.; VODOVOZOVA ELENA L.; MÉSZÁROS TAMÁS; SZEBENI JANOS; GRAN: "Hemocompatibility of liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the lipid bilayer", JOURNAL OF CONTROLLED RELEASE, vol. 160, no. 2, 10 June 2012 (2012-06-10), pages 394 - 400, XP028926617, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2011.12.010
Attorney, Agent or Firm:
NISHIZAWA Kazuyoshi et al. (JP)
Download PDF: