Title:
DNA CHIP FOR DETECTING DENTAL CARIES BACTERIA
Document Type and Number:
WIPO Patent Application WO/2018/168816
Kind Code:
A1
Abstract:
Provided is a means/method with which it is possible to quickly and efficiently detect bacteria that cause dental caries and evaluate dental caries. The present invention pertains to a DNA chip, etc., that carries, for example, the following probe (a) and at least one probe from among the following probes (b) and (c). (a) A probe comprising a nucleic acid that hybridizes to 16S rRNA specific to each of one or more oral bacteria to be detected, wherein the probe is any of the following sequences (i)-(iii): (i) at least one sequence selected from base sequences represented by SEQ ID NOS: 2-7; (ii) a complementary sequence of a sequence of (i); or (iii) a sequence substantially identical to a sequence of (i) or (ii). (b) A total amount indicator probe. (c) An absolute amount indicator probe of one type or a plurality of types.
Inventors:
TAKAYAMA KAZUTO (JP)
Application Number:
PCT/JP2018/009620
Publication Date:
September 20, 2018
Filing Date:
March 13, 2018
Export Citation:
Assignee:
G C DENTAL IND CORP (JP)
International Classes:
C12Q1/68; C12M1/00; C12N15/09; G01N33/50; G01N33/53; G01N33/569; G01N37/00
Domestic Patent References:
| WO2016129249A1 | 2016-08-18 | |||
| WO2003106676A1 | 2003-12-24 |
Foreign References:
| JP2017023093A | 2017-02-02 | |||
| JP2008206516A | 2008-09-11 | |||
| JP2015231362A | 2015-12-24 | |||
| JP2017048654A | 2017-03-09 | |||
| JPS51882B1 | 1976-01-12 | |||
| JP2004163211A | 2004-06-10 | |||
| JPH01108928U | 1989-07-24 | |||
| JP2001133453A | 2001-05-18 | |||
| JP2007074950A | 2007-03-29 |
Other References:
GROSS, ERIN L. ET AL.: "Beyond Streptococcus mutans: Dental Caries Onset Linked to Multiple Species by 16S rRNA Community Analysis", PLOS ONE, vol. 7, no. 10, 16 October 2012 (2012-10-16), pages e47722, XP055555951, Retrieved from the Internet
PONTIGO, F. ET AL.: "Molecular phylogeny and a taxonomic proposal for the genus Streptococcus", GENETICS AND MOLECULAR RESEARCH, vol. 14, no. 3, 21 September 2015 (2015-09-21), pages 10905 - 10918, XP055555964, Retrieved from the Internet
EUROPEAN JOURNAL OF DENTISTRY, vol. 1, January 2007 (2007-01-01), pages 31 - 39
ARCHIVES OF ORAL BIOLOGY, vol. 41, 1996, pages 167 - 73
JAPANESE JOURNAL OF BACTERIOLOGY, vol. 56, 2001, pages 334
SCIENCE, vol. 270, 1995, pages 467 - 470
SCIENCE, vol. 251, 1991, pages 767 - 773
See also references of EP 3597770A4
PONTIGO, F. ET AL.: "Molecular phylogeny and a taxonomic proposal for the genus Streptococcus", GENETICS AND MOLECULAR RESEARCH, vol. 14, no. 3, 21 September 2015 (2015-09-21), pages 10905 - 10918, XP055555964, Retrieved from the Internet
EUROPEAN JOURNAL OF DENTISTRY, vol. 1, January 2007 (2007-01-01), pages 31 - 39
ARCHIVES OF ORAL BIOLOGY, vol. 41, 1996, pages 167 - 73
JAPANESE JOURNAL OF BACTERIOLOGY, vol. 56, 2001, pages 334
SCIENCE, vol. 270, 1995, pages 467 - 470
SCIENCE, vol. 251, 1991, pages 767 - 773
See also references of EP 3597770A4
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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