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Title:
EFFECT OF INHIBITING IMMUNE-RELATED ADVERSE EVENT
Document Type and Number:
WIPO Patent Application WO/2024/004656
Kind Code:
A1
Abstract:
Provided is a pharmaceutical composition that is a composition for treating an immune-related adverse event (irAE) in a subject who has undergone a cancer immunotherapy, the pharmaceutical composition containing anthracycline.

Inventors:
KODAMA TETSUYA (JP)
MORI SHIRO (JP)
Application Number:
PCT/JP2023/022100
Publication Date:
January 04, 2024
Filing Date:
June 14, 2023
Export Citation:
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Assignee:
UNIV TOHOKU (JP)
International Classes:
A61K31/704; A61K39/395; A61K45/00; A61P1/02; A61P7/00; A61P7/06; A61P9/14; A61P11/00; A61P13/12; A61P17/04; A61P17/14; A61P19/02; A61P25/00; A61P35/00; A61P37/02; A61P43/00
Foreign References:
JP2018500384A2018-01-11
Other References:
HAVERKOS BRAD, ZAIN JASMINE, KAMDAR MANALI, NEUWELT ALEXANDER, BAIR STEVEN M., JASEM JAGAR, BERENS EMILY, SMITH CLAYTON, ABBOTT DI: "A Pilot Study Using Nivolumab in Combination with Standard of Care Chemotherapy in Newly Diagnosed Peripheral T-Cell Lymphomas", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 138, no. Supplement 1, 5 November 2021 (2021-11-05), US , pages 2444 - 2444, XP093119257, ISSN: 0006-4971, DOI: 10.1182/blood-2021-152617
LI XIA, WANG XIUPENG, QIAN GUOWEN, ITO ATSUO: "Synergistical chemotherapy and cancer immunotherapy using dual drug-delivering and immunopotentiating mesoporous silica", APPLIED MATERIALS, ELSEVIER, NL, vol. 16, 1 September 2019 (2019-09-01), NL , pages 102 - 111, XP093119259, ISSN: 2352-9407, DOI: 10.1016/j.apmt.2019.05.006
SIRAIT-FISCHER EVELYN, OLESCH CATHERINE, FINK ANNIKA F., BERKEFELD MATTHIAS, HUARD ARNAUD, SCHMID TOBIAS, TAKEDA KAZUHIKO, BRÜNE B: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model", FRONTIERS IN ONCOLOGY, FRONTIERS RESEARCH FOUNDATION, CH, vol. 10, 10 September 2020 (2020-09-10), CH , pages 1771, XP093119261, ISSN: 2234-943X, DOI: 10.3389/fonc.2020.01771
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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