Title:
FERROPORTIN INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2017/068089
Kind Code:
A9
Abstract:
The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
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Inventors:
DÜRRENBERGER FRANZ (CH)
BUHR WILM (DE)
BURCKHARDT SUSANNA (CH)
BURGERT MICHAEL (DE)
KALOGERAKIS ARIS (CH)
REIM STEFAN (CH)
MANOLOVA VANIA (CH)
BOYCE SUSAN (DE)
YARNOLD CHRISTOPHER JOHN (GB)
PENA PAULA (GB)
SHEPHERD JON (GB)
LECCI CRISTINA (GB)
JARJES-PIKE RICHARD (GB)
SCOTT JOHN (GB)
BUHR WILM (DE)
BURCKHARDT SUSANNA (CH)
BURGERT MICHAEL (DE)
KALOGERAKIS ARIS (CH)
REIM STEFAN (CH)
MANOLOVA VANIA (CH)
BOYCE SUSAN (DE)
YARNOLD CHRISTOPHER JOHN (GB)
PENA PAULA (GB)
SHEPHERD JON (GB)
LECCI CRISTINA (GB)
JARJES-PIKE RICHARD (GB)
SCOTT JOHN (GB)
Application Number:
PCT/EP2016/075305
Publication Date:
September 14, 2017
Filing Date:
October 21, 2016
Export Citation:
Assignee:
VIFOR (INTERNATIONAL) AG (CH)
International Classes:
A61K31/4184; A61K31/427; A61K31/4355; A61K31/437; A61K31/4375; A61K31/4439; A61K31/444; A61K31/497; A61K31/4985; A61K31/501; A61K31/506; A61K31/5377; A61K31/55; A61P3/12; A61P7/06; A61P25/16; A61P25/28; A61P31/04
Attorney, Agent or Firm:
GILLE HRABAL (DE)
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