Title:
FLAVONOL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN DETECTION OF BIOLOGICAL MERCAPTAN
Document Type and Number:
WIPO Patent Application WO/2023/097820
Kind Code:
A1
Abstract:
The present invention belongs to the technical field of advanced new materials, and relates to a flavonol compound, and a preparation method therefor and the use thereof in the detection of biological mercaptan. The chemical structure thereof is as shown in formula I: R1 is selected from a strong electron-withdrawing group; and R2 is selected from H, an aryl group, a substituted aryl group, a furyl group, a substituted furyl group, a thienyl group, and a substituted thienyl group. The flavonol compound is used as a fluorescent probe, has the property of stable recognition of cysteine and homocysteine, and has the advantages of high sensitivity, good selectivity, low cost, etc.
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Inventors:
LV CHAO (CN)
LI YING (CN)
FU CHENXI (CN)
ZHANG BING (CN)
CUI LEILEI (CN)
QI JINGQI (CN)
WEI YUXIA (CN)
LI YING (CN)
FU CHENXI (CN)
ZHANG BING (CN)
CUI LEILEI (CN)
QI JINGQI (CN)
WEI YUXIA (CN)
Application Number:
PCT/CN2021/140609
Publication Date:
June 08, 2023
Filing Date:
December 22, 2021
Export Citation:
Assignee:
UNIV DEZHOU (CN)
International Classes:
C07D409/04; C09K11/06; G01N21/64
Foreign References:
| CN110016008A | 2019-07-16 | |||
| CN110894193A | 2020-03-20 |
Other References:
CAO XIAO-YAN, LU HONG-ZHAO, ZHANG QIANG, REN CHUAN-QING, XIA DONG-HUI, LIU JIAN-LI: "Design and Synthesis of a Flavone-based Fluorescent Probe for Cysteine Detection and Its Application in Living Cells Imaging", CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, vol. 48, no. 8, 1 August 2020 (2020-08-01), pages 1033 - 1040, XP093071337, DOI: 10.19756/j.issn.0253鄄3820.191686
HU, YUN ET AL.: "Synthesis and Properties of a Highly Selective Flavonol-based Fluorescent Probe for the Detection of Cysteine", CHINESE JOURNAL OF ANALYSIS LABORATORY, vol. 37, no. 7, 31 July 2018 (2018-07-31), XP009546839
HU, YUN ET AL.: "Synthesis and Properties of a Highly Selective Flavonol-based Fluorescent Probe for the Detection of Cysteine", CHINESE JOURNAL OF ANALYSIS LABORATORY, vol. 37, no. 7, 31 July 2018 (2018-07-31), XP009546839
Attorney, Agent or Firm:
JINAN SHENGDA INTELLECTUAL PROPERTY AGENCY CO.,LTD. (CN)
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