Title:
FLUORESCENT STAINING METHOD
Document Type and Number:
WIPO Patent Application WO/2023/132337
Kind Code:
A1
Abstract:
The present invention develops a fluorescent staining method which is compatible with PAS staining that is a specialized staining technique for staining a substance containing a glycol group, such as a structure containing a polysaccharide in a large amount (e.g., a mucosal fluid, a basement membrane) and which enables clear three-dimensional observation. The present invention provides a method for fluorescently staining a substance containing a glycol group in a tissue or a cell sample, the method including bringing the tissue or the cell sample into contact with a compound represented by general formula (I) or a salt thereof.
Inventors:
NOJIMA SATOSHI (JP)
MORII EIICHI (JP)
SUZUKI YUKI (JP)
MINOURA ITSUSHI (JP)
MORII EIICHI (JP)
SUZUKI YUKI (JP)
MINOURA ITSUSHI (JP)
Application Number:
PCT/JP2023/000031
Publication Date:
July 13, 2023
Filing Date:
January 05, 2023
Export Citation:
Assignee:
UNIV OSAKA (JP)
GORYO CHEMICAL INC (JP)
GORYO CHEMICAL INC (JP)
International Classes:
G01N33/48; C07D311/82; G01N33/15; G01N33/50
Domestic Patent References:
| WO2018174253A1 | 2018-09-27 | |||
| WO2008105376A1 | 2008-09-04 |
Foreign References:
| US4213904A | 1980-07-22 | |||
| US20110039277A1 | 2011-02-17 | |||
| JP2018162986A | 2018-10-18 | |||
| JP2004510767A | 2004-04-08 | |||
| US20070178601A1 | 2007-08-02 | |||
| US20160178637A1 | 2016-06-23 | |||
| CN110954517A | 2020-04-03 | |||
| JPH11508277A | 1999-07-21 | |||
| US20100130505A1 | 2010-05-27 | |||
| US20140323699A1 | 2014-10-30 |
Other References:
NOJIMA SATOSHI, SUSAKI ETSUO A., YOSHIDA KYOTARO, TAKEMOTO HIROYOSHI, TSUJIMURA NAOTO, IIJIMA SHOHEI, TAKACHI KO, NAKAHARA YUJIRO,: "CUBIC pathology: three-dimensional imaging for pathological diagnosis", SCIENTIFIC REPORTS, vol. 7, no. 1, 24 August 2017 (2017-08-24), pages 9269, XP093076266, DOI: 10.1038/s41598-017-09117-0
NOJIMA SATOSHI, ISHIDA SHOICHI, TERAYAMA KEI, MATSUMOTO KATSUHIKO, MATSUI TAKAHIRO, TAHARA SHINICHIRO, OHSHIMA KENJI, KIYOKAWA HIR: "A Novel Three-Dimensional Imaging System Based on Polysaccharide Staining for Accurate Histopathological Diagnosis of Inflammatory Bowel Diseases", CMGH CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, vol. 14, no. 4, 1 January 2022 (2022-01-01), pages 905 - 924, XP093076268, ISSN: 2352-345X, DOI: 10.1016/j.jcmgh.2022.07.001
SATOSHI NOJIMA ET AL., SCIENTIFIC REPORTS, vol. 7, 2014, pages 9269
SATOSHI NOJIMA ET AL., SCIENTIFIC REPORTS, vol. 7, 2017, pages 9269
TAINAKA K ET AL., CELL, vol. 159, 2014, pages 911 - 924
DOBT HU, NAT METHODS, vol. 4, 2007, pages 331 - 336
ERTURK A, NAT PROTOC, vol. 7, 2012, pages 1983 - 1995
PAN C ET AL., NAT METHODS, vol. 13, 2016, pages 859 - 867
HAMA H ET AL., NAT NEUROSCI, vol. 14, 2011, pages 1481 - 1488
KE MT ET AL., NAT NEUROSCI, vol. 16, 2013, pages 1154 - 1161
CHUNG K ET AL., NATURE, vol. 497, 2013, pages 332 - 7
TOMER R ET AL., NAT PROTOC, vol. 9, 2014, pages 1682 - 97
ORGANIC LETTERS, vol. 22, 2020, pages 6035 - 6040
SYNTHESIS, vol. 4, 2007, pages 547 - 550
INDIAN JOURNAL OF CHEMISTRY, vol. 52B, 2013, pages 1152 - 1156
CHEMICAL PAPERS, vol. 72, 2018, pages 1265 - 1276
MOLECULAR DIVERSITY, vol. 19, 2015, pages 263 - 272
J. AM. CHEM. SOC., vol. 127, 2005, pages 4888
ANALYTICAL CHEMISTRY, vol. 70, 1998, pages 2446
NOJIMA SATOSHI, ISHIDA SHOICHI, TERAYAMA KEI, MATSUMOTO KATSUHIKO, MATSUI TAKAHIRO, TAHARA SHINICHIRO, OHSHIMA KENJI, KIYOKAWA HIR: "A Novel Three-Dimensional Imaging System Based on Polysaccharide Staining for Accurate Histopathological Diagnosis of Inflammatory Bowel Diseases", CMGH CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, vol. 14, no. 4, 1 January 2022 (2022-01-01), pages 905 - 924, XP093076268, ISSN: 2352-345X, DOI: 10.1016/j.jcmgh.2022.07.001
SATOSHI NOJIMA ET AL., SCIENTIFIC REPORTS, vol. 7, 2014, pages 9269
SATOSHI NOJIMA ET AL., SCIENTIFIC REPORTS, vol. 7, 2017, pages 9269
TAINAKA K ET AL., CELL, vol. 159, 2014, pages 911 - 924
DOBT HU, NAT METHODS, vol. 4, 2007, pages 331 - 336
ERTURK A, NAT PROTOC, vol. 7, 2012, pages 1983 - 1995
PAN C ET AL., NAT METHODS, vol. 13, 2016, pages 859 - 867
HAMA H ET AL., NAT NEUROSCI, vol. 14, 2011, pages 1481 - 1488
KE MT ET AL., NAT NEUROSCI, vol. 16, 2013, pages 1154 - 1161
CHUNG K ET AL., NATURE, vol. 497, 2013, pages 332 - 7
TOMER R ET AL., NAT PROTOC, vol. 9, 2014, pages 1682 - 97
ORGANIC LETTERS, vol. 22, 2020, pages 6035 - 6040
SYNTHESIS, vol. 4, 2007, pages 547 - 550
INDIAN JOURNAL OF CHEMISTRY, vol. 52B, 2013, pages 1152 - 1156
CHEMICAL PAPERS, vol. 72, 2018, pages 1265 - 1276
MOLECULAR DIVERSITY, vol. 19, 2015, pages 263 - 272
J. AM. CHEM. SOC., vol. 127, 2005, pages 4888
ANALYTICAL CHEMISTRY, vol. 70, 1998, pages 2446
Attorney, Agent or Firm:
MOMII Takafumi (JP)
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