Title:
FLUOROALKENE COMPOUND PRECURSOR, METHOD FOR SYNTHESIZING PRECURSOR, AND METHOD FOR PREPARING FLUOROALKENE COMPOUND BY USING PRECURSOR
Document Type and Number:
WIPO Patent Application WO/2020/242046
Kind Code:
A1
Abstract:
The present invention relates to a technique for efficiently synthesizing a fluoroalkene compound and, more specifically, to: a fluoroalkene compound precursor capable of efficiently synthesizing various types of fluoroalkene compounds; a method for synthesizing the precursor; and a method for preparing a fluoroalkene compound by using the precursor. According to the present invention, fluoroalkene compounds into which various types of aryl groups are introduced can be very efficiently synthesized and can be readily prepared at low cost.
Inventors:
LEE SUN WOO (KR)
Application Number:
PCT/KR2020/004938
Publication Date:
December 03, 2020
Filing Date:
April 10, 2020
Export Citation:
Assignee:
UNIV NAT CHONNAM IND FOUND (KR)
International Classes:
C07C22/08; B01J23/50; B01J31/22
Foreign References:
| US2804484A | 1957-08-27 |
Other References:
I, Y. ET AL.: "Silver-Assisted Difunctionalization of Terminal Alkynes: Highly Regio- and Stereoselective Synthesis of Bromofluoroalkenes", ADV. SYNTH. CATAL., vol. 354, 2012, pages 2683 - 2688, XP055770097
DAS, J. P ET AL.: "Catalytic Hunsdiecker Reaction of alpha,beta-Unsaturated Carboxylic Acids: How Efficient Is the Catalyst?", J. ORG. CHEM., vol. 67, 2002, pages 7861 - 7864, XP002656407, DOI: 10.1021/JO025868H
MALO-FOREST, B. ET AL.: "Synthesis and growth inhibition activity of fluorinated derivatives of tamoxifen", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, 2013, pages 1712 - 1715, XP028986037, DOI: 10.1016/j.bmcl.2013.01.057
NAHRA, F. ET AL.: "Hydrofluorination of Alkynes Catalysed by GoldBifluorides", CHEMCATCHEM, vol. 7, 2015, pages 240 - 244, XP055770101
JAYARAMAN, A. ET AL.: "Silver-Mediated Decarboxylative Fluorodiiodination of AlkynoicAcids: Synthesis of Regio- and Stereoselective Fluoroalkenes", ORG LETT., vol. 21, no. 10, 2019, pages 3485 - 3489, XP055770104
JAYARAMAN, A. ET AL.: "Synthesis of l-Fluoro-2,2-diiodovinylarenes via Decarboxylation of Alkynoic Acids and Their Coupling Reactions", 123RD GENERAL MEETING OF THE KOREAN CHEMICAL SOCIETY., 2019
DAS, J. P ET AL.: "Catalytic Hunsdiecker Reaction of alpha,beta-Unsaturated Carboxylic Acids: How Efficient Is the Catalyst?", J. ORG. CHEM., vol. 67, 2002, pages 7861 - 7864, XP002656407, DOI: 10.1021/JO025868H
MALO-FOREST, B. ET AL.: "Synthesis and growth inhibition activity of fluorinated derivatives of tamoxifen", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, 2013, pages 1712 - 1715, XP028986037, DOI: 10.1016/j.bmcl.2013.01.057
NAHRA, F. ET AL.: "Hydrofluorination of Alkynes Catalysed by GoldBifluorides", CHEMCATCHEM, vol. 7, 2015, pages 240 - 244, XP055770101
JAYARAMAN, A. ET AL.: "Silver-Mediated Decarboxylative Fluorodiiodination of AlkynoicAcids: Synthesis of Regio- and Stereoselective Fluoroalkenes", ORG LETT., vol. 21, no. 10, 2019, pages 3485 - 3489, XP055770104
JAYARAMAN, A. ET AL.: "Synthesis of l-Fluoro-2,2-diiodovinylarenes via Decarboxylation of Alkynoic Acids and Their Coupling Reactions", 123RD GENERAL MEETING OF THE KOREAN CHEMICAL SOCIETY., 2019
Attorney, Agent or Firm:
IAM PATENT & LAW FIRM (KR)
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