Title:
FORMULATION CONTAINING EMRICASAN
Document Type and Number:
WIPO Patent Application WO/2020/004652
Kind Code:
A1
Abstract:
The present disclosure provides a formulation having improved solubility and/or stability of emricasan. In one embodiment, the present disclosure provides a formulation containing (i) emricasan or a derivative thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, (ii) a nonionic surfactant including a polyoxyethylene group, and (iii) a buffering agent that maintains the pH at about 4.5 to about 8.5. The present disclosure also provides a composition in the form of powder for preparing such a formulation at the time of use.
Inventors:
KOIZUMI NORIKO (JP)
OKUMURA NAOKI (JP)
OKUMURA NAOKI (JP)
Application Number:
PCT/JP2019/025945
Publication Date:
January 02, 2020
Filing Date:
June 28, 2019
Export Citation:
Assignee:
THE DOSHISHA (JP)
International Classes:
A61K38/05; A61K9/08; A61K9/14; A61K47/02; A61K47/14; A61K47/26; A61K47/34; A61P27/02
Domestic Patent References:
| WO2017110094A1 | 2017-06-29 | |||
| WO2017129585A1 | 2017-08-03 | |||
| WO2017222370A1 | 2017-12-28 | |||
| WO2017110094A1 | 2017-06-29 |
Foreign References:
| JP2017515854A | 2017-06-15 | |||
| JP2017507165A | 2017-03-16 | |||
| JP2015501828A | 2015-01-19 | |||
| JP2018125234A | 2018-08-09 |
Other References:
EDITED BY JAPAN PHARMACEUTICAL ADDITIVES ASSOCIATION: "Passages, Pharmaceutical additives encyclopedia 2016", PHARMACEUTICAL ADDITIVES ENCYCLOPEDIA 2016, 2016, pages 155, 536, 537, XP009524926, ISBN: 978-4-8408-1329-7
Attorney, Agent or Firm:
YAMAMOTO Shusaku et al. (JP)
Download PDF:
Previous Patent: SENSOR, INPUT DEVICE, AND ELECTRONIC APPARATUS
Next Patent: FINE BUBBLE GENERATION DEVICE AND FINE BUBBLE GENERATION METHOD
Next Patent: FINE BUBBLE GENERATION DEVICE AND FINE BUBBLE GENERATION METHOD