Title:
FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2017/193913
Kind Code:
A1
Abstract:
Provided are a fosaprepitant phosphate intermediate (IV) preparation method, a fosaprepitant phosphate intermediate (IV-A) and a method (AA) for preparing fosaprepitant dimeglumine by using the intermediate (IV-A). IV: R1 and R2 are independently selected from C1-C7 alkyl groups or benzyl groups; IV-A: R1 and R2 are independently selected from C1-C7 alkyl groups or benzyl groups, and R1 and R2 are not both benzyl groups.
Inventors:
ZHANG JICHENG (CN)
LI ZENG (CN)
HUANG LUNING (CN)
CHEN QIAN (CN)
TAO ANPING (CN)
GU HONG (CN)
LI ZENG (CN)
HUANG LUNING (CN)
CHEN QIAN (CN)
TAO ANPING (CN)
GU HONG (CN)
Application Number:
PCT/CN2017/083630
Publication Date:
November 16, 2017
Filing Date:
May 09, 2017
Export Citation:
Assignee:
ZHEJIANG HUAHAI PHARM CO LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
International Classes:
C07F9/6558; C07C213/08; C07C215/10
Domestic Patent References:
| WO2010018595A2 | 2010-02-18 | |||
| WO2010018595A2 | 2010-02-18 | |||
| WO2011045817A2 | 2011-04-21 |
Foreign References:
| CN104098604A | 2014-10-15 | |||
| CN104650142A | 2015-05-27 | |||
| CN1075812C | 2001-12-05 |
Other References:
See also references of EP 3456726A4
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
Download PDF: