Title:
FUNCTIONAL CLONING OF GENES ENCODING PROTEINS/ENZYMES INVOLVED IN PROTEOLYTIC CLEAVAGE
Document Type and Number:
WIPO Patent Application WO2001029232
Kind Code:
A9
Abstract:
This invention concerns methods and means for the functional cloning of genes encoding proteins or enzymes involved in proteolytic cleavage. The invention is based on the use of caspase expression cassettes comprising the coding sequence of a proteolytic cleavage site flanked by sequences encoding two caspase subunits.
Inventors:
CORDELL BARBARA (US)
LI YONGHONG (US)
LI YONGHONG (US)
Application Number:
PCT/US2000/028941
Publication Date:
August 15, 2002
Filing Date:
October 19, 2000
Export Citation:
Assignee:
SCIOS INC (US)
CORDELL BARBARA (US)
LI YONGHONG (US)
CORDELL BARBARA (US)
LI YONGHONG (US)
International Classes:
C12N9/64; C12N15/10; A61K48/00; (IPC1-7): C12N15/62; A61K48/00; C07K19/00; C12N9/64; C12Q1/37; C12Q1/68
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