FUSOSOME COMPOSITIONS FOR CNS DELIVERY - FLAGSHIP PIONEERING INNOVATIONS V INC

Title:

FUSOSOME COMPOSITIONS FOR CNS DELIVERY

Document Type and Number:

WIPO Patent Application WO/2020/102499

Kind Code:

A3

Abstract:

The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a fusogen, a positive target cell- specific regulatory element, and a non-target cell- specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.

More Like This:

WO/2008/050807	METHOD FOR PRODUCTION OF LIPOSOME PREPARATION
WO/1996/010390	NOVEL COMPOSITIONS FOR THE INTRODUCTION OF POLYANIONIC MATERIALS INTO CELLS
WO/2023/160702	AMINO LIPID COMPOUND, PREPARATION METHOD THEREFOR, COMPOSITION THEREOF AND USE THEREOF

Inventors:

VON MALTZAHN GEOFFREY (US)
RUBENS JACOB (US)
SHAH JAGESH (US)
RUZO MATIAS ALBERT (US)
PUCCI FERDINANDO (US)
MILWID JOHN (US)
MEE MICHAEL (US)
GORDON NEAL (US)

Application Number:

PCT/US2019/061424

Publication Date:

July 23, 2020

Filing Date:

November 14, 2019

Export Citation:

Click for automatic bibliography generation Help

Assignee:

FLAGSHIP PIONEERING INNOVATIONS V INC (US)

International Classes:

A61K9/127; C12N15/88

Domestic Patent References:

WO2010053489A1	2010-05-14
WO2006078221A1	2006-07-27

Foreign References:

US20050070493A1

2005-03-31

Attorney, Agent or Firm:

KOYFMAN, Hannah, R. et al. (US)

Download PDF:

View/Download PDF PDF Help

Previous Patent: CHAIN MAIL SURGICAL COLLAR AND METHOD OF PERCUTANEOUS DEVICE STABILIZATION THEREWITH

Next Patent: SAW CHAIN HOLDER AND SHARPENING ASSEMBLY HAVING A SAW CHAIN HOLDER