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Title:
GLUT-1 AS A RECEPTOR FOR HTLV ENVELOPES AND ITS USES
Document Type and Number:
WIPO Patent Application WO2004096841
Kind Code:
A8
Abstract:
The invention relates to the use of the ubiquitous vertebrate glucose transporter GLUT1, or of fragments or sequences derived thereof, for the in vitro diagnosis of cancers, when used as a tumor marker, or for the screening of compounds useful for the preparation of drugs for the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV, or pathologies linked to an overexpression of GLUT1 on cell surfaces, or the in vitro detection of GLUT1 on cell surfaces. The invention also relates to pharmaceutical compositions containing GLUT1, or fragments or sequences derived thereof, and to their uses such as in the frame of the prevention or the treatment of pathologies linked to an infection of an individual with a PTLV.

Inventors:
BATTINI JEAN-LUC GEORGES LAURE (FR)
MANEL NICOLAS GABRIEL ALBERT (FR)
KIM FELIX JINHYUN (US)
KINET SANDRINA (FR)
TAYLOR NAOMI (FR)
SITBON MARC (FR)
Application Number:
PCT/EP2004/004624
Publication Date:
January 19, 2006
Filing Date:
April 30, 2004
Export Citation:
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Assignee:
CENTRE NAT RECH SCIENT (FR)
UNIV MONTPELLIER II (FR)
BATTINI JEAN-LUC GEORGES LAURE (FR)
MANEL NICOLAS GABRIEL ALBERT (FR)
KIM FELIX JINHYUN (US)
KINET SANDRINA (FR)
TAYLOR NAOMI (FR)
SITBON MARC (FR)
International Classes:
A61K38/16; A61K38/28; C07K14/15; C07K14/62; C07K14/705; G01N33/566; (IPC1-7): C07K14/15; A61K38/16; C07K14/47; G01N33/574
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