Title:
A GLYCOPEPTIDE AND PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO2001079267
Kind Code:
A9
Abstract:
The stereospecific synthesis of a glycopeptide using a triply orthogonal protection scheme is described, in particular, the synthesis of N-acetylglucosaminyl- beta -(1,4)-N-acetylmuramylmonopeptide and derivatives thereof. The glycopeptide is useful for the preparation of N-acetylglulosaminyl-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds having a glucosaminyl- beta -(1,4)-N-acetylmuramic acid disaccharide core.
Inventors:
BLASZCZAK LARRY CHRIS (US)
DINGESS-HAMMOND ELIZABETH ANNE (US)
HORNBACK WILLIAM JOSEPH (US)
VANNIEUWENHZE MICHAEL SCOTT (US)
DINGESS-HAMMOND ELIZABETH ANNE (US)
HORNBACK WILLIAM JOSEPH (US)
VANNIEUWENHZE MICHAEL SCOTT (US)
Application Number:
PCT/US2001/012630
Publication Date:
October 23, 2003
Filing Date:
April 18, 2001
Export Citation:
Assignee:
LILLY CO ELI (US)
BLASZCZAK LARRY CHRIS (US)
DINGESS-HAMMOND ELIZABETH ANNE (US)
HORNBACK WILLIAM JOSEPH (US)
VANNIEUWENHZE MICHAEL SCOTT (US)
BLASZCZAK LARRY CHRIS (US)
DINGESS-HAMMOND ELIZABETH ANNE (US)
HORNBACK WILLIAM JOSEPH (US)
VANNIEUWENHZE MICHAEL SCOTT (US)
International Classes:
C07H15/04; C07K1/06; C07K1/10; C07K5/072; C07K7/06; C07K9/00; A61K38/00; (IPC1-7): C07K9/00
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