Title:
GOODPASTURE ANTIGEN BINDING PROTEIN
Document Type and Number:
WIPO Patent Application WO2000050607
Kind Code:
A3
Abstract:
The present invention provides isolated nucleic acid sequences and expression vectors encoding the Goodpasture antigen binding protein (GPBP), substantially purified GPBP, antibodies against GPBP, and methods for detecting GPBP.
Inventors:
SAUS JUAN (ES)
Application Number:
PCT/IB2000/000324
Publication Date:
November 30, 2000
Filing Date:
February 24, 2000
Export Citation:
Assignee:
SAUS JUAN (ES)
International Classes:
A61K38/00; A61K39/00; A61P35/00; A61P37/00; A61P37/06; C07K14/47; C07K16/18; C07K16/40; G01N33/50; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/12; C12N15/09; C12N15/54; C12P21/08; C12Q1/02; C12Q1/68; G01N33/15; G01N33/53; G01N33/564; (IPC1-7): C12N15/54; C12N9/12; C07K16/40; C12Q1/48; C12Q1/68; A61K38/45
Foreign References:
| US5424408A | 1995-06-13 |
Other References:
REVERT FERNANDO ET AL: "Phosphorylation of the Goodpasture Antigen by Type A Protein Kinases.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 22, 1995, pages 13254 - 13261, XP002145904, ISSN: 0021-9258
PENADES JOSE R ET AL: "Characterization and expression of multiple alternatively spliced transcripts of the Goodpasture antigen gene region: Goodpasture antibodies recognize recombinant proteins representing the autoantigen and one of its alternative forms.", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 229, no. 3, 1995, pages 754 - 760, XP000938485, ISSN: 0014-2956
HENDERSON R D ET AL: "Goodpasteure's syndrome associated with multiple sclerosis.", ACTA NEUROLOGICA SCANDINAVICA, vol. 98, no. 2, August 1998 (1998-08-01), pages 134 - 135, XP000938488, ISSN: 0001-6314
KALLURI R ET AL: "THE GOODPASTURE AUTOANTIGEN STRUCTURAL DELINEATION OF TWO IMMUNOLOGICALLY PRIVILEGED EPITOPES ON A3(IV) CHAIN OF TYPE IV COLLAGEN", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 113, no. 17, 12 April 1996 (1996-04-12), pages 9062 - 9068, XP000882924, ISSN: 0021-9258
RAYA ANGEL ET AL: "Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 18, 30 April 1999 (1999-04-30), pages 12642 - 12649, XP002145905, ISSN: 0021-9258
PENADES JOSE R ET AL: "Characterization and expression of multiple alternatively spliced transcripts of the Goodpasture antigen gene region: Goodpasture antibodies recognize recombinant proteins representing the autoantigen and one of its alternative forms.", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 229, no. 3, 1995, pages 754 - 760, XP000938485, ISSN: 0014-2956
HENDERSON R D ET AL: "Goodpasteure's syndrome associated with multiple sclerosis.", ACTA NEUROLOGICA SCANDINAVICA, vol. 98, no. 2, August 1998 (1998-08-01), pages 134 - 135, XP000938488, ISSN: 0001-6314
KALLURI R ET AL: "THE GOODPASTURE AUTOANTIGEN STRUCTURAL DELINEATION OF TWO IMMUNOLOGICALLY PRIVILEGED EPITOPES ON A3(IV) CHAIN OF TYPE IV COLLAGEN", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 113, no. 17, 12 April 1996 (1996-04-12), pages 9062 - 9068, XP000882924, ISSN: 0021-9258
RAYA ANGEL ET AL: "Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 18, 30 April 1999 (1999-04-30), pages 12642 - 12649, XP002145905, ISSN: 0021-9258
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