Title:
GPCR REGULATOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/202582
Kind Code:
A1
Abstract:
A compound of a GPR132 regulator, a pharmaceutically acceptable salt or ester, a prodrug, a stereoisomer, a hydrate, a solvate, a crystal form, or a metabolite form thereof, as well as a preparation method therefor and medicinal use thereof.
Inventors:
JIAO NING (CN)
SUN JINPENG (CN)
YU XIAO (CN)
DOU XIAODONG (CN)
XU GUOFENG (CN)
CHENG JIE (CN)
HUO TONGYU (CN)
GAO MINGXIN (CN)
ZHAO XINYI (CN)
WANG JIALE (CN)
ZHANG CAIFANG (CN)
LIU YAMENG (CN)
SUN JINPENG (CN)
YU XIAO (CN)
DOU XIAODONG (CN)
XU GUOFENG (CN)
CHENG JIE (CN)
HUO TONGYU (CN)
GAO MINGXIN (CN)
ZHAO XINYI (CN)
WANG JIALE (CN)
ZHANG CAIFANG (CN)
LIU YAMENG (CN)
Application Number:
PCT/CN2023/089013
Publication Date:
October 26, 2023
Filing Date:
April 18, 2023
Export Citation:
Assignee:
BEIJING CHANGPING LABORATORY (CN)
UNIV BEIJING (CN)
UNIV BEIJING (CN)
International Classes:
C07D307/85; A61K31/343; A61K31/443; A61P1/18; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P35/00; A61P37/02; C07D209/42; C07D333/70; C07D401/12; C07D405/12; C07D417/12
Foreign References:
| CN115215823A | 2022-10-21 | |||
| CN105085450A | 2015-11-25 | |||
| CN109705071A | 2019-05-03 | |||
| US20130059858A1 | 2013-03-07 | |||
| US20130053345A1 | 2013-02-28 | |||
| US20210095293A1 | 2021-04-01 |
Other References:
DATABASE Registry CAS; 19 December 2022 (2022-12-19), ANONYMOUS : "2-Benzofurancarboxylic acid, 3-methyl-5-[[[2- [4-(trifluoromethyl)- 2- thiazolyl]ethyl]amin o]sulfonyl]-", XP093102445, retrieved from STN Database accession no. 2871435-85-5
DATABASE Registry CAS; 24 November 2020 (2020-11-24), ANONYMOUS : "1H-Indole-2-carboxylic a cid, 5-[(cyclopropyla mino)sulfonyl]-3-me thyl-", XP093102447, retrieved from STN Database accession no. 2528192-96-1
SHEHATA MOHAMED A., BELCIK CHRISTENSEN HANNA, ISBERG VIGNIR, SEJER PEDERSEN DANIEL, BENDER ANDREAS, BRÄUNER-OSBORNE HANS, GLORIAM : "Identification of the first surrogate agonists for the G protein-coupled receptor GPR132", RSC ADVANCES, vol. 5, no. 60, 1 January 2015 (2015-01-01), pages 48551 - 48557, XP093102140, DOI: 10.1039/C5RA04804D
DATABASE Registry CAS; 24 November 2020 (2020-11-24), ANONYMOUS : "1H-Indole-2-carboxylic a cid, 5-[(cyclopropyla mino)sulfonyl]-3-me thyl-", XP093102447, retrieved from STN Database accession no. 2528192-96-1
SHEHATA MOHAMED A., BELCIK CHRISTENSEN HANNA, ISBERG VIGNIR, SEJER PEDERSEN DANIEL, BENDER ANDREAS, BRÄUNER-OSBORNE HANS, GLORIAM : "Identification of the first surrogate agonists for the G protein-coupled receptor GPR132", RSC ADVANCES, vol. 5, no. 60, 1 January 2015 (2015-01-01), pages 48551 - 48557, XP093102140, DOI: 10.1039/C5RA04804D
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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