Title:
HAIR GROWING AGENT
Document Type and Number:
WIPO Patent Application WO/2014/092007
Kind Code:
A1
Abstract:
Provided is a hair growing agent which contains, as an active ingredient, a pyrazolopyrimidine derivative that is represented by general formula (1) and has excellent hair growing effect. (In the formula, R1 represents a hydrogen atom or a protective group of a phenolic hydroxyl group; and each of R2 and R3 independently represents a saturated halogenoalkyl group.)
Inventors:
YOSHIKAWA MASAAKI (JP)
HOU I-CHING (JP)
HOU I-CHING (JP)
Application Number:
PCT/JP2013/082781
Publication Date:
June 19, 2014
Filing Date:
December 06, 2013
Export Citation:
Assignee:
NIPPON SUPPLEMENT INC (JP)
International Classes:
A61K31/519; A61K8/49; A61K8/97; A61K36/81; A61K45/00; A61P17/14; A61Q7/00
Other References:
DR. COMPTON ET AL.: "Pyrazolo[1,5-a] pyrimidines: Estrogen Receptor Ligands Possessing Estrogen Receptor Antagonist Activity", JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, no. 24, 2004, pages 5872 - 5893
THORNTON MJ ET AL.: "Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin", EXPERIMENTAL DERMATOLOGY, vol. 12, no. 2, 2003, pages 181 - 190
HS. OH, RC. SMART: "An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, no. 22, 1996, pages 12525 - 12530
THORNTON MJ ET AL.: "Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin", EXPERIMENTAL DERMATOLOGY, vol. 12, no. 2, 2003, pages 181 - 190
HS. OH, RC. SMART: "An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, no. 22, 1996, pages 12525 - 12530
Attorney, Agent or Firm:
KAWAMURA, Kiyoshi et al. (JP)
Kiyoshi Kawamura (JP)
Kiyoshi Kawamura (JP)
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