Title:
HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/143763
Kind Code:
A1
Abstract:
The present invention relates to the technical field of medicine. Specifically, the present invention relates to haloallylamine compounds as represented by formula (I) or pharmaceutically acceptable salts, esters, stereoisomers and tautomers thereof, and pharmaceutical preparations and pharmaceutical compositions containing these compounds, as well as their application in preventing and/or treating diseases related to or mediated by SSAO/VAP-1 protein, wherein R1, R2, R3, R4, R5, R6, L1, and Cy1 are defined in the specification.
Inventors:
WAN ZHONGHUI (CN)
LI LIN (CN)
WU FRANK (CN)
LI LIN (CN)
WU FRANK (CN)
Application Number:
PCT/CN2020/071405
Publication Date:
July 16, 2020
Filing Date:
January 10, 2020
Export Citation:
Assignee:
NANJING TRANSTHERA BIOSCIENCES CO LTD (CN)
International Classes:
C07D471/04; A61K31/472; A61P3/00
Domestic Patent References:
| WO2018028517A1 | 2018-02-15 | |||
| WO2013163675A1 | 2013-11-07 | |||
| WO2019129213A1 | 2019-07-04 | |||
| WO2018196677A1 | 2018-11-01 | |||
| WO2019101086A1 | 2019-05-31 | |||
| WO2007120528A2 | 2007-10-25 | |||
| WO2018151985A1 | 2018-08-23 | |||
| WO2013163675A1 | 2013-11-07 |
Foreign References:
| CN109988106A | 2019-07-09 |
Other References:
TETRAHEDRON LETTERS, vol. 32, 1985, pages 3807 - 3810
See also references of EP 3892621A4
See also references of EP 3892621A4
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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