Title:
KETAMINE PAMOATE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/143762
Kind Code:
A1
Abstract:
Provided are pamoate salts of ketamine having a stoichiometry of 2: 1 of ketamine to pamoate, including R, S-ketamine pamoate, S-ketamine pamoate, or R-ketamine pamoate, and crystalline or amorphous forms of the pamoate salts, and having excellent safety and properties for pharmaceutical applications. Also provided are pharmaceutical compositions including the pamoate salts of ketamine and their uses in treating a CNS disease or serving as an anesthetic.
Inventors:
LIN TONG-HO (CN)
WEN YUNG-SHUN (CN)
CHEN CHIA-HSIEN (CN)
CHANG WEI-JU (CN)
WEN YUNG-SHUN (CN)
CHEN CHIA-HSIEN (CN)
CHANG WEI-JU (CN)
Application Number:
PCT/CN2020/071404
Publication Date:
July 16, 2020
Filing Date:
January 10, 2020
Export Citation:
Assignee:
ALAR PHARMACEUTICALS INC (CN)
International Classes:
C07C255/20; A61K31/135; A61P25/24
Domestic Patent References:
| WO2018122626A1 | 2018-07-05 |
Foreign References:
| US20140178480A1 | 2014-06-26 | |||
| US20080293695A1 | 2008-11-27 | |||
| CN106562952A | 2017-04-19 |
Other References:
See also references of EP 3908570A4
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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