HALOGENATING AGENT AND PROCESS FOR HALOGENATING HYDROXYL GROUP

WIPO Patent Application WO/1999/041214

A1

A halogenating agent represented by general formula (1) and a process for halogenating a hydroxyl group therewith. In said formula R?1¿ and R?2¿ are the same or different and each represents ethyl, propyl, isopropyl, butyl, isobutyl or allyl; X represents chloro or bromo; and Y represents chloride, bromide, dichlorophosphate, dibromophosphate, chlorosulfonate, bromosulfonate, chlorooxalate or bromooxalate ion.

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SUZUKI DAISUKE (JP)
KIKUCHI RYO (JP)
YASUI MASARU (JP)

PCT/JP1998/005579

August 19, 1999

December 10, 1998

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OTSUKA KAGAKU KK (JP)
SUZUKI DAISUKE (JP)
KIKUCHI RYO (JP)
YASUI MASARU (JP)

C07B39/00; C07C17/16; C07C25/02; C07C25/22; C07C257/02; (IPC1-7): C07B39/00

DODS R. F., ROTH J. S.: "THE REACTION OF ARSENIC TRIHALIDES WITH NUCLEOSIDES. HALOMETHYLENE DIMETHYLAMMONIUMHALIDE. A NEW HALOGENATING AGENT FOR NUCLEOSIDES.", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 34., no. 06., 1 June 1969 (1969-06-01), US, pages 1627 - 1630., XP002920027, ISSN: 0022-3263, DOI: 10.1021/jo01258a020
DODS R. F., ROTH J. S.: "HALOGENATION OF NUCLEOSIDES BY (HALOMETHYLENE) DIMETHYLENE AMMONIUM HALIDES.", TETRAHEDRON LETTERS, PERGAMON, GB, no. 03., 1 January 1969 (1969-01-01), GB, pages 165 - 168., XP002920028, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(01)87499-2

Tamura, Iwao (Terauchi 1-chome Toyonaka-shi Osaka-fu, JP)

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