Title:
HAPTEN, ARTIFICIAL ANTIGEN, AND ANTIBODY OF TOXOFLAVIN, SYNTHETIC METHODS THERFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/248317
Kind Code:
A1
Abstract:
Disclosed are methods for preparing a hapten of toxoflavin and an artificial antigen of toxoflavin, wherein a highly specific and sensitive antibody can be obtained from an animal immunized with the prepared artificial antigen. The antigen and antibody prepared and the treatment of a sample by means of this method can provide a simple and quick technical approach for the highly sensitive detection of toxoflavin.
Inventors:
KE YUEBIN (CN)
LI JINFENG (CN)
LI CHENGYAO (CN)
DING YE (CN)
ZHAO FANG (CN)
LIU BOCHAO (CN)
LI JINFENG (CN)
LI CHENGYAO (CN)
DING YE (CN)
ZHAO FANG (CN)
LIU BOCHAO (CN)
Application Number:
PCT/CN2019/095190
Publication Date:
December 17, 2020
Filing Date:
July 09, 2019
Export Citation:
Assignee:
SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION SHENZHEN HEALTH INSPECTION CENTER SHENZHEN INST O (CN)
International Classes:
C07D487/04; C07K14/765; C07K14/77; C07K14/795; C07K16/44; G01N33/53; G01N33/532; G01N33/558; G01N33/58
Foreign References:
| CN105974018A | 2016-09-28 | |||
| CN109824673A | 2019-05-31 | |||
| CN108120832A | 2018-06-05 | |||
| CN102161662A | 2011-08-24 |
Other References:
WENG, CHENHUI ET AL.: "Advances in the synthesis, separation and detection technology of toxoflavin", CHINESE BULLETIN OF LIFE SCIENCES, vol. 29, no. 4, 30 April 2017 (2017-04-30), DOI: 20200210131701A
BRUGGEMAN YVONNE E. ET AL.: "Regulation of the flavin redox potential by flavin-binding antibodies", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 249, 31 December 1997 (1997-12-31), XP002364940, DOI: 20200210132025A
BRUGGEMAN YVONNE E. ET AL.: "Regulation of the flavin redox potential by flavin-binding antibodies", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 249, 31 December 1997 (1997-12-31), XP002364940, DOI: 20200210132025A
Attorney, Agent or Firm:
YOGO PATENT & TRADE MARK AGENCY LIMITED COMPANY (CN)
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