HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS - BEIJING INNOCARE PHARMA TECH CO LTD

Title:

HETEROCYCLIC COMPOUNDS AS BTK INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2022/037649

Kind Code:

A1

Abstract:

Disclosed are heterocyclic compounds of formula (I) or their pharmaceutically acceptable salts used as inhibitors of Bruton's tyrosine kinase (BTK) and its C481 mutant. Disclosed also are methods for preparing compounds of formula (I) or their pharmaceutically acceptable salts. Those compounds can be used to treat and/or prevent related diseases mediated by BTK or its C481 mutant, especially cancer and autoimmune diseases.

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Inventors:

CHEN XIANGYANG (CN)
PANG YUCHENG (CN)

Application Number:

PCT/CN2021/113535

Publication Date:

February 24, 2022

Filing Date:

August 19, 2021

Export Citation:

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Assignee:

BEIJING INNOCARE PHARMA TECH CO LTD (CN)

International Classes:

C07D487/04; A61K31/519; A61K31/5377; A61P29/00; A61P35/00; A61P35/02; A61P37/02

Domestic Patent References:

WO2021180107A1	2021-09-16
WO2020150681A1	2020-07-23
WO2020015735A1	2020-01-23
WO2020063012A1	2020-04-02
WO2015132799A2	2015-09-11
WO2015189620A1	2015-12-17
WO2017046604A1	2017-03-23

Attorney, Agent or Firm:

INTELIGHT IP LAW FIRM (CN)

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