Title:
HETEROCYCLIC COMPOUNDS AS KRAS G12C INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2022/222871
Kind Code:
A1
Abstract:
Provided are compounds of general Formula (I) and their pharmaceutically acceptable salts suitable for inhibiting or regulating the activity of KRAS G12C. Said compounds are useful for preventing and /or treating relevant KRAS G12C mediated cancers. Also provided are preparation methods thereof.
Inventors:
CHEN XIANGYANG (CN)
PANG YUCHENG (CN)
PANG YUCHENG (CN)
Application Number:
PCT/CN2022/087197
Publication Date:
October 27, 2022
Filing Date:
April 15, 2022
Export Citation:
Assignee:
BEIJING INNOCARE PHARMA TECH CO LTD (CN)
International Classes:
C07D471/04; A61K31/4353; A61K31/495; A61K31/53; A61P35/00; C07D403/14
Domestic Patent References:
| WO2019141250A1 | 2019-07-25 | |||
| WO2020259432A1 | 2020-12-30 |
Foreign References:
| CN111051306A | 2020-04-21 | |||
| CN111253397A | 2020-06-09 |
Attorney, Agent or Firm:
INTELIGHT IP LAW FIRM (CN)
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