Title:
HETEROCYCLIC DERIVATIVE AS INHIBITOR, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/002223
Kind Code:
A1
Abstract:
The present invention relates to a heterocyclic derivative as an inhibitor, a method for preparing same, and use thereof. In particular, the present invention relates to a compound represented by general formula (I), a method for preparing same, a pharmaceutical composition comprising the compound, and use thereof as an inhibitor in preparing a medicament for treating and/or preventing cancers and diseases related to achondroplasia.
Inventors:
ZENG MI (CN)
GAO PENG (CN)
ZENG MINGGAO (CN)
DU JIANGANG (CN)
CHENG YU (CN)
YU WENSHENG (CN)
GAO PENG (CN)
ZENG MINGGAO (CN)
DU JIANGANG (CN)
CHENG YU (CN)
YU WENSHENG (CN)
Application Number:
PCT/CN2023/103743
Publication Date:
January 04, 2024
Filing Date:
June 29, 2023
Export Citation:
Assignee:
SHANGHAI HANSOH BIOMEDICAL CO LTD (CN)
JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD (CN)
JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
C07D207/10; A61K31/415; A61K31/506; A61P19/00; A61P35/00; A61P35/02; C07D213/40; C07D231/12; C07D401/12; C07D403/12; C07D405/04; C07D417/12
Foreign References:
| CN115772161A | 2023-03-10 | |||
| CN108026050A | 2018-05-11 | |||
| CN101006061A | 2007-07-25 | |||
| US20110230536A1 | 2011-09-22 | |||
| CN114126620A | 2022-03-01 |
Other References:
ZHU, WEI ET AL.: "Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer", JOURNAL OF MEDICINAL CHEMISTRY, vol. 60, no. 14, 22 June 2017 (2017-06-22), XP055948920, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.7b00076
LEE SU-LIN, HSU EN-CHI, CHOU CHIH-CHIEN, CHUANG HSIAO-CHING, BAI LI-YUAN, KULP SAMUEL K., CHEN CHING-SHIH: "Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 54, no. 18, 22 September 2011 (2011-09-22), US , pages 6364 - 6374, XP093122931, ISSN: 0022-2623, DOI: 10.1021/jm2007744
LEE SU-LIN, HSU EN-CHI, CHOU CHIH-CHIEN, CHUANG HSIAO-CHING, BAI LI-YUAN, KULP SAMUEL K., CHEN CHING-SHIH: "Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 54, no. 18, 22 September 2011 (2011-09-22), US , pages 6364 - 6374, XP093122931, ISSN: 0022-2623, DOI: 10.1021/jm2007744
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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