Title:
HETEROCYCLIC DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2018/199291
Kind Code:
A1
Abstract:
The purpose of the present invention is to discover a novel compound having an excellent β-lactamase-inhibiting activity, and to provide a useful prophylactic or therapeutic agent for bacterial infectious diseases which comprises a combination of the compound with a β-lactam-type drug or the compound alone. A compound represented by formula (1a) or (1b) [in formulae (1a) and (1b), X represents an oxygen atom, a sulfur atom or -NRa1-, G represents a 4- to 20-membered nitrogenated non-aryl hetero ring which may be substituted, or a 5- or 6-membered nitrogenated heteroaryl group which may be substituted, and other groups are as defined in the description] or a pharmaceutically acceptable salt thereof.
Inventors:
KOIKE SACHIKO (JP)
TAKAI KENTARO (JP)
MIZUSHIMA SHINGO (JP)
KANAI TOSHIO (JP)
TAKAI KENTARO (JP)
MIZUSHIMA SHINGO (JP)
KANAI TOSHIO (JP)
Application Number:
PCT/JP2018/017204
Publication Date:
November 01, 2018
Filing Date:
April 27, 2018
Export Citation:
Assignee:
SUMITOMO DAINIPPON PHARMA CO LTD (JP)
International Classes:
C07F5/02; A61K31/545; A61K31/546; A61K31/69; A61K45/00; A61P1/16; A61P7/00; A61P9/00; A61P11/00; A61P13/02; A61P15/00; A61P17/00; A61P17/02; A61P19/02; A61P27/02; A61P27/16; A61P29/00; A61P31/04; A61P31/10; A61P31/12; A61P37/08; A61P43/00; C07F5/04
Domestic Patent References:
| WO2015179308A1 | 2015-11-26 | |||
| WO2016003929A1 | 2016-01-07 |
Foreign References:
| JP2016506419A | 2016-03-03 | |||
| JP2016502973A | 2016-02-01 |
Attorney, Agent or Firm:
YAMAMOTO Shusaku et al. (JP)
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