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Title:
HIGH-FREQUENCY BIPOLAR UNRECOVERABLE ELECTROPORATION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2021/114219
Kind Code:
A1
Abstract:
A high-frequency bipolar unrecoverable electroporation system. The system comprises an upper layer information management module, a lower computer control module and a bipolar high-voltage pulse discharging circuit, wherein the upper layer information management module receives set working parameters and then transmits same to the lower computer control module, and then generates a control signal and transmits same to the bipolar high-voltage pulse discharging circuit so as to produce a bipolar high-voltage pulse. Compared with a conventional unipolar irreversible electroporation pulse sequence, the high-frequency bipolar unrecoverable electroporation system can better and more uniformly increase the induced transmembrane potential of tightly arrayed cells to a simulation electroporation threshold, such that an ablation region is more uniform. The high-frequency bipolar unrecoverable electroporation system can achieve a better tumor ablation effect and the aim of restraining the growth of tumors, and has better safety and validity.

Inventors:
ZHANG XIAOCHEN (CN)
XUE ZHIXIAO (CN)
LI HONGGANG (CN)
Application Number:
PCT/CN2019/125104
Publication Date:
June 17, 2021
Filing Date:
December 13, 2019
Export Citation:
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Assignee:
TIANJIN INTELLIGENT HEALTH CO LTD (CN)
International Classes:
A61B18/00
Foreign References:
CN105055015A2015-11-18
CN106388932A2017-02-15
CN109394334A2019-03-01
CN109628438A2019-04-16
CN109124760A2019-01-04
CN104684500A2015-06-03
CN1345610A2002-04-24
US20100023004A12010-01-28
Attorney, Agent or Firm:
CNCLOUD INTELLECTUAL PROPERTY LAW FIRM (CN)
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