Title:
HIGH-STABILITY DAPTOMYCIN COMPOSITION FOR INJECTION, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/160531
Kind Code:
A1
Abstract:
Disclosed are a high-stability daptomycin composition for injection, and a preparation method therefor. The daptomycin composition for injection comprises daptomycin and a pharmaceutically acceptable carrier, and the pharmaceutically acceptable carrier contains a divalent metal salt, a pH regulator, and an osmotic pressure regulator; and the molar ratio of daptomycin to divalent metal salt in the daptomycin composition for injection is 1: 1.0 to 1: 3.5. The composition can be used for preparing antibacterial drugs.
Inventors:
YUAN XIYING (CN)
WANG WEIBAO (CN)
WU GUOFENG (CN)
YE LILI (CN)
WU JIALI (CN)
CAI JINGJING (CN)
PAN YIBIN (CN)
ZHA JUAN (CN)
GAO ZHONGMING (CN)
SUN QIMING (CN)
HE YIMIN (CN)
WANG ZUOLIANG (CN)
PING JIANHONG (CN)
WANG WEIBAO (CN)
WU GUOFENG (CN)
YE LILI (CN)
WU JIALI (CN)
CAI JINGJING (CN)
PAN YIBIN (CN)
ZHA JUAN (CN)
GAO ZHONGMING (CN)
SUN QIMING (CN)
HE YIMIN (CN)
WANG ZUOLIANG (CN)
PING JIANHONG (CN)
Application Number:
PCT/CN2021/096559
Publication Date:
August 04, 2022
Filing Date:
May 27, 2021
Export Citation:
Assignee:
ZHEJIANG NOVUS PHARMACEUTICALS CO LTD (CN)
ZHEJIANG MED XINCHANG PHARM (CN)
ZHEJIANG MED XINCHANG PHARM (CN)
International Classes:
A61K38/12; A61K9/14; A61K9/19; A61K47/02; A61P31/04
Foreign References:
| CN110339342A | 2019-10-18 | |||
| CN110339341A | 2019-10-18 | |||
| CN111053746A | 2020-04-24 | |||
| CN1616083A | 2005-05-18 | |||
| CN111093625A | 2020-05-01 |
Attorney, Agent or Firm:
FAITHFULAW INTERNATIONAL IP LAW OFFICE (CN)
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