Title:
HOMOLACTIC FERMENTATION FROM PENTOSE
Document Type and Number:
WIPO Patent Application WO/2010/095600
Kind Code:
A1
Abstract:
Disclosed is a lactic acid bacterium capable of homolactic fermentation using a pentose as a substrate. The lactic acid bacterium can utilize a pentose. In the lactic acid bacterium, the phosphoketolase pathway is blocked and the pentose phosphate pathway is activated. Also disclosed is a method for producing lactic acid from a pentose using the lactic acid bacterium. Further disclosed is a method for producing the lactic acid bacterium.
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Inventors:
KONDO AKIHIKO (JP)
OKANO KENJI (JP)
NODA HIDEO (JP)
OKANO KENJI (JP)
NODA HIDEO (JP)
Application Number:
PCT/JP2010/052216
Publication Date:
August 26, 2010
Filing Date:
February 15, 2010
Export Citation:
Assignee:
KANSAI CHEM ENG (JP)
BIO ENERGY CORP (JP)
KOBE UNIVESITY (JP)
KONDO AKIHIKO (JP)
OKANO KENJI (JP)
NODA HIDEO (JP)
BIO ENERGY CORP (JP)
KOBE UNIVESITY (JP)
KONDO AKIHIKO (JP)
OKANO KENJI (JP)
NODA HIDEO (JP)
International Classes:
C12N1/21; C12P7/56; C12N15/09
Other References:
KOBAR, L. ET AL.: "Stoichiometry of glucose and xylose fermentation in Butyrivibrio Fibrisolvens 787.", UKRAINSKII BIOKHIMICHESKII ZHURNAL, vol. 68, 1996, pages 85 - 89
POSTHUMA, C.C. ET AL.: "Expression of the xylulose 5-phosphate phosphoketolase gene, xpkA, from Lactobacillus pentosus MD363 is induced by sugars that are fermented via the phospholetolase pathway and is repressed by glucose mediated by CcpA and the mannose phosphoenolpyruvate phosphotransferase system.", APPL.ENV.MICROBIOL., vol. 68, no. 2, 2002, pages 831 - 837
TANAKA, K. ET AL.: "Two different pathways tor D-xylose metabolism and the effect of xylose concentration on the yield coefficient of L-lactate in mixed-acid fermentation by the lactic acid bacterium Lactococcus lactiis IO-1.", APPL.MICROBIOL.BIOTECHNOL., vol. 60, 2002, pages 160 - 167
OKANO, K. ET AL.: "Homo-D-lactic acid fermentation from arabinose by redirection of the phosphoketolase pathway to the pentose phosphate tathway in L-lactate dehydrogenase gene-deficient Lactobacillus plantarum.", APPL.ENV.MICROBIOL., vol. 75, no. 15, August 2009 (2009-08-01), pages 5175 - 5178
OKANO, K. ET AL.: "Efficient production of optically pure D-lactic acid from raw corn starch by using a genetically modified L-lactate dehydrogenase gene-deficient and a-amylase-secreting Lactobacillus plantarum strain.", APPL.ENV.MICROBIOL., vol. 75, no. 2, January 2009 (2009-01-01), pages 462 - 467
POSTHUMA, C.C. ET AL.: "Expression of the xylulose 5-phosphate phosphoketolase gene, xpkA, from Lactobacillus pentosus MD363 is induced by sugars that are fermented via the phospholetolase pathway and is repressed by glucose mediated by CcpA and the mannose phosphoenolpyruvate phosphotransferase system.", APPL.ENV.MICROBIOL., vol. 68, no. 2, 2002, pages 831 - 837
TANAKA, K. ET AL.: "Two different pathways tor D-xylose metabolism and the effect of xylose concentration on the yield coefficient of L-lactate in mixed-acid fermentation by the lactic acid bacterium Lactococcus lactiis IO-1.", APPL.MICROBIOL.BIOTECHNOL., vol. 60, 2002, pages 160 - 167
OKANO, K. ET AL.: "Homo-D-lactic acid fermentation from arabinose by redirection of the phosphoketolase pathway to the pentose phosphate tathway in L-lactate dehydrogenase gene-deficient Lactobacillus plantarum.", APPL.ENV.MICROBIOL., vol. 75, no. 15, August 2009 (2009-08-01), pages 5175 - 5178
OKANO, K. ET AL.: "Efficient production of optically pure D-lactic acid from raw corn starch by using a genetically modified L-lactate dehydrogenase gene-deficient and a-amylase-secreting Lactobacillus plantarum strain.", APPL.ENV.MICROBIOL., vol. 75, no. 2, January 2009 (2009-01-01), pages 462 - 467
Attorney, Agent or Firm:
NANJO, Hiromichi et al. (JP)
Hiromichi Nanjo (JP)
Hiromichi Nanjo (JP)
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