Title:
HYPONATREMIA REMEDIES
Document Type and Number:
WIPO Patent Application WO/1999/005146
Kind Code:
A1
Abstract:
Hyponatremia remedies containing as the active ingredient opioid $g(k) receptor agonists represented by general formula (I) or the like; and a method of treatment therewith. The agonists exhibit both the property as a hydragogue diuretic of specifically excreting water and the effect of keeping blood sodium level, which is not linked up with the diuretic action, and cause only negligible adverse effects, thus being ideal hyponatremia remedies useful for the drug therapy of hyponatremia.
Inventors:
NAGASE HIROSHI (JP)
UENO KOKI (JP)
HAGIMOTO KOJI (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAWAMURA KUNIAKI (JP)
SHIRAKI MOTOHIRO (JP)
UENO KOKI (JP)
HAGIMOTO KOJI (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAWAMURA KUNIAKI (JP)
SHIRAKI MOTOHIRO (JP)
Application Number:
PCT/JP1998/000800
Publication Date:
February 04, 1999
Filing Date:
February 26, 1998
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
NAGASE HIROSHI (JP)
UENO KOKI (JP)
HAGIMOTO KOJI (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAWAMURA KUNIAKI (JP)
SHIRAKI MOTOHIRO (JP)
NAGASE HIROSHI (JP)
UENO KOKI (JP)
HAGIMOTO KOJI (JP)
ENDOH TAKASHI (JP)
TANAKA TOSHIAKI (JP)
KAWAMURA KUNIAKI (JP)
SHIRAKI MOTOHIRO (JP)
International Classes:
A61K31/435; C07D489/00; (IPC1-7): C07D489/00; A61K31/435
Domestic Patent References:
| WO1993015081A1 | 1993-08-05 |
Foreign References:
| JPH01149788A | 1989-06-12 | |||
| JPS61271275A | 1986-12-01 |
Download PDF:
Previous Patent: METHOD FOR TRIOXAN ISOLATION
Next Patent: THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME
Next Patent: THIAZOLOBENZOHETEROCYCLES, PREPARATION AND MEDICINES CONTAINING SAME