Title:
IDENTIFICATION OF DIET-REGULATED DISEASE-ASSOCIATED GENES
Document Type and Number:
WIPO Patent Application WO2004042013
Kind Code:
A3
Abstract:
The invention encompasses identification of diet-regulated disease-associated genes and EST's and methods of use in disease screening, monitoring and treatment. It also encompasses methods for formulating medical foods used to treat and prevent disease and slow disease progression. A new method of identifying diet-regulated disease-associated genes and EST's is disclosed that employs gene expression analysis in inbred strains of mice and matching the results with publicly available QTL ( quantitative trait locus) information.
Inventors:
KAPUT JAMES (US)
Application Number:
PCT/US2003/034524
Publication Date:
October 28, 2004
Filing Date:
October 31, 2003
Export Citation:
Assignee:
KAPUT JAMES (US)
International Classes:
A23L33/00; A61K47/00; C12M1/34; C12Q1/68; C12N; (IPC1-7): C12Q1/68
Other References:
ELLIOTT ET AL: "F1Fo-ATPase Subunit e Gene Isolated in a Screen for Diet Regulated Genes", BIOCHEM. AND BIOPHYSICAL RES. COMM., vol. 190, no. 1, January 1993 (1993-01-01), pages 167 - 174, XP002981979
RIOUX ET AL: "Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci", AM. J. OF HUMAN GENETICS, vol. 66, 2000, pages 1863 - 1870, XP001016365
See also references of EP 1558763A4
RIOUX ET AL: "Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci", AM. J. OF HUMAN GENETICS, vol. 66, 2000, pages 1863 - 1870, XP001016365
See also references of EP 1558763A4
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