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Title:
IKZF2 DEGRADATION AGENT, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/155710
Kind Code:
A1
Abstract:
The present invention belongs to the field of medicinal chemistry, and relates to an IKZF2 degradation agent, a pharmaceutical composition comprising same and use thereof. Specifically, the IKZF2 degradation agent has a structure represented by formula (I), and can be used to prevent, ameliorate and/or treat IKAROS family zinc finger 2 (IKZF2)-related diseases or disorders.

Inventors:
MEI DESHENG (CN)
WU XIONG (CN)
LV SHIMING (CN)
LING XIN (CN)
XIAO CHENG (CN)
SUN GAORUI (CN)
LIU SHUAISHUAI (CN)
TAN XIAOHUA (CN)
ZHANG YARU (CN)
Application Number:
PCT/CN2023/074793
Publication Date:
August 24, 2023
Filing Date:
February 07, 2023
Export Citation:
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Assignee:
SUZHOU GUOKUANG PHARMTECH CO LTD (CN)
International Classes:
A61K31/454; C07D401/14; A61K31/4545; A61P35/00; C07D401/04; C07D407/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D487/08; C07D495/04; C07D513/04
Domestic Patent References:
WO2020263832A12020-12-30
WO2021087093A12021-05-06
WO2021173995A22021-09-02
WO2021219078A12021-11-04
WO2021260528A12021-12-30
WO2022029573A12022-02-10
WO2022081976A12022-04-21
WO2022232391A12022-11-03
WO2022232536A12022-11-03
WO2023283428A12023-01-12
Foreign References:
CN111051298A2020-04-21
CN111629749A2020-09-04
CN112261970A2021-01-22
CN112334194A2021-02-05
CN113271945A2021-08-17
CN113329792A2021-08-31
CN113372327A2021-09-10
CN113490528A2021-10-08
TW202140441A2021-11-01
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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