Title:
IMIDAZO[1,2-A]PYRIDINE ANXIOLYTICS
Document Type and Number:
WIPO Patent Application WO2005044818
Kind Code:
A3
Abstract:
Imidazo[1,2-a]apyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed. A representative compound of the invention is:
Inventors:
FANG KEVIN (US)
GROVER PAUL (US)
JERUSSI TOM (US)
GROVER PAUL (US)
JERUSSI TOM (US)
Application Number:
PCT/US2004/035822
Publication Date:
June 16, 2005
Filing Date:
October 28, 2004
Export Citation:
Assignee:
SEPRACOR INC (US)
FANG KEVIN (US)
GROVER PAUL (US)
JERUSSI TOM (US)
FANG KEVIN (US)
GROVER PAUL (US)
JERUSSI TOM (US)
International Classes:
A61K31/435; C07D471/04; C07D519/00; (IPC1-7): C07D471/04; A61K31/435
Foreign References:
| US4382938A | 1983-05-10 | |||
| FR2647451A1 | 1990-11-30 |
Other References:
P.GEORGE ET AL.: "Imidazopyridines: Towards Novel Hypnotic and Anxiolytic Drugs", IL FARMACO, vol. 46, no. 1,Suppl., 1991, pages 277 - 288, XP002900937
S.P.GUPTA ET AL.: "Quantitative Stucture-Activity Relationship Studies on some Nonbenzodiazepine Series of Compunds acting at the Benzodiazepin Receptor", BIOORG.MED.CHEM., vol. 6, 1998, pages 2213 - 2218, XP002325731
S.P.GUPTA ET AL.: "Quantitative Stucture-Activity Relationship Studies on some Nonbenzodiazepine Series of Compunds acting at the Benzodiazepin Receptor", BIOORG.MED.CHEM., vol. 6, 1998, pages 2213 - 2218, XP002325731
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