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Patent Searching and Data


Title:
IMMUNOASSAYS FOR TOPIRAMATE
Document Type and Number:
WIPO Patent Application WO2006047450
Kind Code:
A3
Abstract:
Generally, the present invention relates to topiramate analogs that have substituents at the sulfamate group or at the 9-position or 10-position. The topiramate analogs can include immunogenic moieties that can be used to prepare anti-topiramate antibodies, or antigenic moieties that can be used in immunodiagnostic assays for topiramate. Also, the topiramate analog can include tracer moieties for detecting the presence or amount of the analog during an immunodiagnostic assay. Additionally, the topiramate analogs can be used in immunodiagnostic assays to compete with topiramate for binding with anti-topiramate antibodies.

Inventors:
OUYANG ANLONG (US)
ARABSHAHI LILI (US)
Application Number:
PCT/US2005/038257
Publication Date:
November 23, 2006
Filing Date:
October 21, 2005
Export Citation:
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Assignee:
SERADYN INC (US)
OUYANG ANLONG (US)
ARABSHAHI LILI (US)
International Classes:
C07K1/10; G01N33/53; C07K1/13; C07K16/00; C12P7/00; G01N33/532; G01N33/533; G01N33/534; G01N33/546
Foreign References:
US5952187A1999-09-14
US20040258758A12004-12-23
US20030166581A12003-09-04
Other References:
FAIVRE-CHAUVET ET AL.: "Introduction of five potentially metabolizable linking groups between in-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody-II. Comparative pharmacokinetics and biodistribution in human colorectal carcinoma-bearing nude mice", NUCL. MED. BIOL., vol. 20, no. 6, 1993, pages 763 - 771, XP003001781
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