Title:
INDOLONE-SUBSTITUTED-1,3-THIAZOLIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/160708
Kind Code:
A1
Abstract:
Disclosed are an aryl methylene-indolone-3-substituted thiazolidine-ketone derivative, and a preparation method therefor and the use thereof. The compound can be used as a lead compound of a PARP 14 inhibitor.
Inventors:
MENG GE (CN)
GE WEIJUAN (CN)
TONG JING (CN)
CHENG YANAN (CN)
CAO HUILING (CN)
GE WEIJUAN (CN)
TONG JING (CN)
CHENG YANAN (CN)
CAO HUILING (CN)
Application Number:
PCT/CN2023/078485
Publication Date:
August 31, 2023
Filing Date:
February 27, 2023
Export Citation:
Assignee:
UNIV FUDAN (CN)
International Classes:
C07D413/12; A61P35/00
Foreign References:
CN114634496A | 2022-06-17 | |||
CN114634500A | 2022-06-17 | |||
CN114634506A | 2022-06-17 | |||
CN114634501A | 2022-06-17 | |||
CN113636970A | 2021-11-12 | |||
CN111699176A | 2020-09-22 |
Other References:
MANSOUR EMAN, TAHER H. A., EL-FARARGY A. F., ELEWA SAFAA I.: "Synthesis of Some Novel Indoline-2,3-Dione Derivatives and the Influence of Gamma Irradiation on Their Biological Activities", POLYCYCLIC AROMATIC COMPOUNDS, GORDON AND BREACH, NEW YORK, NY, US, vol. 42, no. 10, 26 November 2022 (2022-11-26), US , pages 6846 - 6860, XP093087609, ISSN: 1040-6638, DOI: 10.1080/10406638.2021.1991395
Attorney, Agent or Firm:
WAYNE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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