INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

Title:

INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS

Document Type and Number:

WIPO Patent Application WO1995018830

Kind Code:

A3

Abstract:

The invention relates to nucleic acids encoding novel Kunitz domains which inhibit plasmin. The invention also relates to recombinant expression vectors comprising the nucleic acids, recombinant host cells transformed with these vectors, methods of producing plasmin binding proteins and the use of the proteins for the preparation of a medicament.

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Inventors:

MARKLAND WILLIAM (US)
LADNER ROBERT CHARLES (US)

Application Number:

PCT/US1995/000298

Publication Date:

August 10, 1995

Filing Date:

January 11, 1995

Export Citation:

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Assignee:

PROTEIN ENG CORP (US)
MARKLAND WILLIAM (US)
LADNER ROBERT CHARLES (US)

International Classes:

A61K38/55; A61K38/57; A61K51/00; A61P7/04; C12N15/09; C04B35/593; C07K14/81; C12N9/68; C12Q1/37; C12Q1/56; (IPC1-7): C07K14/81; A61K38/57; C12Q1/37; C12N9/68

Domestic Patent References:

WO1993014122A1

1993-07-22

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