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Title:
INJECTABLE ANTIBACTERIAL POLYMER HYDROGEL, PREPARATION METHOD FOR SAME, AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/166964
Kind Code:
A1
Abstract:
An injectable antibacterial polymer hydrogel, a preparation method for same, and uses thereof. The hydrogel is prepared with an alginate, a hyaluronate, an iron ion-containing compound, and ethylenediaminetetraacetic acid disodium serving as raw materials. The hydrogel is uniform and stable, has excellent self-repairing performance, shear thinning performance, and injectability, and provides excellent bacterial resistance. The hydrogel can be used as an injectable carrier and is applicable in local injection therapies for tissue damages of different sizes and shapes. The hydrogel has simple raw materials, is fast-forming, easy and convenient to prepare, and environmentally friendly, and provides excellent application prospects.

Inventors:
ZHAO HANG (CN)
HAN XIANGLONG (CN)
SHUAI FANGYUAN (CN)
YIN YIJIA (CN)
Application Number:
PCT/CN2022/075399
Publication Date:
August 11, 2022
Filing Date:
February 07, 2022
Export Citation:
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Assignee:
UNIV SICHUAN (CN)
International Classes:
A61K9/06; A61K47/02; A61K47/18; A61K47/36; A61L27/02; A61L27/20; A61L27/52; A61L27/54
Foreign References:
CN114272206A2022-04-05
CN111518289A2020-08-11
CN104804199A2015-07-29
CN109316418A2019-02-12
CN105597156A2016-05-25
Other References:
TORREY HEATHER, KüHTREIBER WILLEM M., OKUBO YOSHIAKI, TRAN LISA, CASE KATHERINE, ZHENG HUI, VANAMEE EVA, FAUSTMAN DENISE L.: "A novel TNFR2 agonist antibody expands highly potent regulatory T cells", SCIENCE SIGNALING, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, US, vol. 13, no. 661, 8 December 2020 (2020-12-08), US , pages eaba9600, XP055820627, ISSN: 1945-0877, DOI: 10.1126/scisignal.aba9600
Attorney, Agent or Firm:
GAOYUNG INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)
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