ISOQUINOLINONE DERIVATIVE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF

WIPO Patent Application WO/2005/014576

A1

A compound of the formula: (wherein the reference marks are as defined in the description), or a salt thereof. There is provided a preventive/therapeutic agent for JNK-associated pathological condition or disorder that exhibits excellent JNK-specific inhibitory activity and excellent oral absorption.

KITAMURA SHUJI (JP)
KAJINO MASAHIRO (JP)
ASANO YASUTOMI (JP)
FUKUMOTO SHOJI (JP)
IGATA HIDEKI (JP)

PCT/JP2004/011738

February 17, 2005

August 10, 2004

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TAKEDA PHARMACEUTICAL (JP)
KITAMURA SHUJI (JP)
KAJINO MASAHIRO (JP)
ASANO YASUTOMI (JP)
FUKUMOTO SHOJI (JP)
IGATA HIDEKI (JP)

A61K31/4725; A61K31/5355; A61K31/5377; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/00; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D217/24; (IPC1-7): C07D401/06; A61K31/4725; A61K31/5355; A61K31/5377; A61P1/04; A61P1/16; A61P3/04; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/00; A61P17/00; A61P17/06; A61P19/02; A61P19/06; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D401/14; C07D405/14; C07D413/06; C07D417/14

WO2003068750A1

2003-08-21

JP2000072751A

2000-03-07

Takashima, Hajime (1-1 Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka, JP)

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