Title:
KERATIN BD-13, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/083203
Kind Code:
A1
Abstract:
Provided are a keratin BD-13, a coding nucleic acid molecule, expression vector, and host cell thereof and a preparation method therefor, and a pharmaceutical composition containing said keratin. Keratin BD-13 can be used to prepare antipyretic and analgesic, antitussive and expectorant, anticonvulsant, antiepileptic, blood pressure lowering, anti-inflammatory and antiviral drugs.
Inventors:
YU SHISHAN (CN)
WANG XIAOLIANG (CN)
LIU YUNBAO (CN)
QU JING (CN)
LI JIANG (CN)
FENG NAN (CN)
LI YONG (CN)
ZHAGN MI (CN)
SU GUOZHU (CN)
WANG XIAOLIANG (CN)
LIU YUNBAO (CN)
QU JING (CN)
LI JIANG (CN)
FENG NAN (CN)
LI YONG (CN)
ZHAGN MI (CN)
SU GUOZHU (CN)
Application Number:
PCT/CN2020/124364
Publication Date:
May 06, 2021
Filing Date:
October 28, 2020
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07K14/47; A61K38/17; A61P9/12; A61P11/10; A61P11/14; A61P25/08; A61P29/00; A61P31/12; C12N15/12; C12N15/63
Foreign References:
| CN1324850A | 2001-12-05 | |||
| CN1324859A | 2001-12-05 | |||
| CN1331144A | 2002-01-16 |
Other References:
DATABASE Nucleotide GenBank; ANONYMOUS: "Bos taurus keratin 86 (KRT86), mRNA", XP055817359, retrieved from NCBI Database accession no. NM_001193068.1
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research overview of the pharmacological action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, CN, vol. 10, no. 28, 5 October 2013 (2013-10-05), CN, pages 23 - 26+33, XP055806914, ISSN: 1673-7210
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
LIU, RUI: "The Antipyretic Effect Evaluation of Water Baffulo Horn and Development of Pearl Product", MEDICINE AND HEALTH SCIENCES, CHINESE MASTER’S THESES FULL-TEXT DATABASE, 15 January 2014 (2014-01-15), pages 1 - 83, XP055813163
See also references of EP 4053152A4
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research overview of the pharmacological action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, CN, vol. 10, no. 28, 5 October 2013 (2013-10-05), CN, pages 23 - 26+33, XP055806914, ISSN: 1673-7210
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
LIU, RUI: "The Antipyretic Effect Evaluation of Water Baffulo Horn and Development of Pearl Product", MEDICINE AND HEALTH SCIENCES, CHINESE MASTER’S THESES FULL-TEXT DATABASE, 15 January 2014 (2014-01-15), pages 1 - 83, XP055813163
See also references of EP 4053152A4
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