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Title:
KERATIN YK93-8, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/074104
Kind Code:
A1
Abstract:
The present invention belongs to the field of biopharmaceuticals. Provided in the present invention are keratin YK93-8, a nucleic acid molecule encoding same, an expression vector containing the nucleic acid molecule, a host cell containing the expression vector or a host cell having the the nucleic acid molecule integrated into the genome, as well as a method for preparing keratin YK93-8 and a pharmaceutical composition of keratin YK93-8. Further provided is the use of the above-mentioned keratin YK93-8 and other products in the preparation of drugs, such as a drug for treating hyperplasia of prostate, lymphoma, melanoma, breast cancer, lung cancer and uterine myoma, an analgesic, a lactation drug and a coagulant.

Inventors:
YU SHISHAN (CN)
CHEN XIAOGUANG (CN)
JIN JING (CN)
LIU YUNBAO (CN)
LI MI (CN)
LI YONG (CN)
JIANG HUIMIN (CN)
WANG XIAOJING (CN)
SHI GUORU (CN)
HAO MENGYAO (CN)
MA SHUANGGANG (CN)
QU JING (CN)
LI SHUYING (CN)
WANG MINGJIN (CN)
SU GUOZHU (CN)
FU JIANG (CN)
Application Number:
PCT/CN2023/121527
Publication Date:
April 11, 2024
Filing Date:
September 26, 2023
Export Citation:
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Assignee:
INST MATERIA MEDICA CAMS (CN)
International Classes:
C07K14/47; A61K38/17; A61P13/08; A61P15/14; A61P29/00; A61P35/00; C12N1/21; C12N15/12; C12N15/70; C12P21/02
Domestic Patent References:
WO2021211059A12021-10-21
Foreign References:
CN112724226A2021-04-30
CN102590530A2012-07-18
CN116535486A2023-08-04
Other References:
DATABASE Protein 28 October 2020 (2020-10-28), ANONYMOUS: "keratin, type II cuticular Hb4 [Manis pentadactyla]", XP093156227, Database accession no. XP_036771059.1
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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