Title:
KERATINOCYTE PROLIFERATION INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2002/048136
Kind Code:
A1
Abstract:
Keratinocyte proliferation inhibitors containing one or more zearalenones as the active ingredient; remedies or preventives for skin diseases in association with the abnormal proliferation of keratinocytes; a method of inhibiting the proliferation of keratinocytes which comprises using one or more zearalenones in an efficacious dose; a method of treating or preventing skin diseases in association with the abnormal proliferation of keratinocytes which comprises administering one or more zearalenones in an efficacious dose to patients with a need therefor; kits for inhibiting the proliferation of keratinocytes which consist of one or more zearalenones in an efficacious dose and a manual; kits for treating or preventing skin diseases in association with the abnormal proliferation of keratinocytes; and utilization of one or more zearalenones for producing keratinocyte proliferation inhibitors or remedies or preventives for skin diseases in association with the abnormal proliferation of keratinocytes.
Inventors:
TSUCHIYA MASAYUKI (JP)
OHTOMO TOSHIHIKO (JP)
OHTOMO TOSHIHIKO (JP)
Application Number:
PCT/JP2001/010928
Publication Date:
June 20, 2002
Filing Date:
December 13, 2001
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
TSUCHIYA MASAYUKI (JP)
OHTOMO TOSHIHIKO (JP)
TSUCHIYA MASAYUKI (JP)
OHTOMO TOSHIHIKO (JP)
International Classes:
A61K31/335; A61K31/365; A61P17/00; A61P17/02; A61P17/06; A61P29/00; A61P37/02; A61P37/08; C07D313/00; (IPC1-7): C07D313/00; A61K31/365; A61P17/00; A61P17/02; A61P17/06; A61P29/00; A61P37/02; A61P37/08
Domestic Patent References:
| WO1996013259A2 | 1996-05-09 | |||
| WO1998004264A1 | 1998-02-05 |
Foreign References:
| EP0606044A1 | 1994-07-13 | |||
| JPH0840893A | 1996-02-13 | |||
| EP0646576A1 | 1995-04-05 |
Attorney, Agent or Firm:
Shamoto, Ichio (New Ohtemachi Bldg. 2-1 Ohtemachi 2-chome Chiyoda-ku, Tokyo, JP)
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